Elad Gil is a serial entrepreneur, executive, and one of the greatest tech investors of all time, with early stakes in something like 40 billion-plus dollar companies: AirBnB, Anduril, Coinbase, Figma, Flexport, Instacart, Notion, OpenDoor, Pinterest, Square, Stripe… I could really go on. He’s now managing a new billion dollar venture fund, for which he’s the sole investor.

Erik Torenberg is a technology entrepreneur and investor.

Presently, he’s the founder of Turpentine. Previously, he was the chairman of On Deck, co-founder and general partner at Village Global, and first employee at Product Hunt.

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Bryan Johnson is the world's most measured human. Johnson sold his company, Braintree Venmo, to PayPal for $800m in 2013. Through his Project Blueprint, Johnson has achieved metabolic health equal to the top 1.5% of 18 year olds, inflammation 66% lower than the average 10 year old, and reduced his speed of aging by the equivalent of 31 years.

Johnson freely shares his protocols and data publicly for everyone to use. Project Blueprint, is an endeavor to achieve humanity and earth scale cooperation starting within Self.

In 2023, Johnson launched Rejuvenation Olympics, a leaderboard assessing one's speed of aging using DNA methylation. Of the 1,750 people who have been using this state-of-the-art aging algorithm to track their progress longitudinally, Johnson ranks #1 in speed of age reduction.

Johnson is also the founder & CEO of Kernel, creator of the world’s first mainstream non-invasive neuroimaging system; and OS Fund, where he invested $100M in the predictable engineering of atoms, molecules, and organisms into companies now collectively valued over $6B. He is an outdoor adventure enthusiast, pilot, and author of children’s books, Code 7 and The Proto Project.

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Anthony “Pomp” Pompliano is an entrepreneur and technology investor. He runs his family office which makes private investments, along with owning majority stakes in a number of operating businesses.

Additionally, Pomp hosts popular conversations on “The Pomp Podcast,” which has been downloaded more than 50 million times. Pomp also writes a letter that is read by more than 250,000 investors each morning.

Pomp’s interests lie at the intersection of finance, technology, entrepreneurship, and economics, which he tweets about extensively to his more than 1.6 million followers.

0:00 - Intro

3:11 - Incumbents and Competition in the Age of AI

5:12 - Media’s Relationship with Technology

9:48 - Individuals vs Institutions and the Future of Content

11:46 - Consensus, Truth, and Misinformation

15:47 - How to Cut Through the Noise

18:47 - The Decline of Trust in Institutions

24:10 - Balancing Optimism and Cynicism

26:46 - National Debt

33:22 - Bad Legislation, Bad Politicians, and Bad Incentives

37:54 - Growing Our Way Out of the Problem

42:19 - Autonomous Cars, Pig Heart Transplants, and How Innovation Propagates Itself

49:22 - Legislating Technology

55:04 - Increasing the Number of Entrepreneurs in Society

1:03:08 - When Better Technology Doesn’t Mean Better Outcomes

1:05:24 - Talent Allocation

1:10:56 - What Does Pomp Do Every Day?

1:19:52 - Lessons From 1300 Interviews

1:21:56 - On Fame, Audience, and Parasocial Relationships

1:29:23 - The State of Crypto

1:34:14 - Institutional Adoption of Crypto

1:37:20 - Is Slow-Moving Bureaucracy a Bug or a Feature?

1:42:02 - Remote Work and Regulatory Arbitrage

1:46:22 - Promising Cities and the Internet as an Equalizer

1:50:03 - Lessons From War

1:58:07 - What Should More People Be Thinking About?

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Bryan Caplan is a Professor of Economics at George Mason University and a New York Times Bestselling author.

He’s the author of 8 books, including The Myth of the Rational Voter, The Case Against Education, and Open Borders: The Science and Ethics of Immigration. His next book, Build, Baby, Build: The Science and Ethics of Housing, will be published by the Cato Institute in 2024.

He’s the editor and chief writer for Bet On It, the blog hosted by the Salem Center for Policy at the University of Texas. He’s published in the New York Times, Washington Post, Wall Street Journal, TIME, Newsweek, Atlantic, American Economic Review, Economic Journal, Journal of Law and Economics, and Intelligence, blogged for EconLog from 2005-2022, and appeared on ABC, BBC, Fox News, MSNBC, and C-SPAN.

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Delian Asparouhov is the co-founder, President and Chairman of Varda Space Industries, a company building spacecraft to manufacture materials in microgravity that are difficult or impossible to produce on Earth— starting with pharmaceuticals. He’s also a Partner at Founders Fund.

Previously, he was a principal at Khosla Ventures, head of growth at Teespring, and founder of a healthcare company called Nightingale. Delian is Bulgarian, attended MIT, and likes to ski and play soccer.

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Robin Hanson is a professor at George Mason University and researcher at the Future of Humanity Institute at Oxford.

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Chris Mason is a professor of Genomics, Physiology, and Biophysics at Weill Cornell Medicine. He is also one of the founding Directors of the WorldQuant Initiative for Quantitative Prediction.

He is the author of The Next 500 Years: Engineering Life to Reach New Worlds, and the co-author of The Age of Prediction: Algorithms, AI, and the Shifting Shadows of Risk.

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Keith Rabois is a General Partner at Founders Fund and the CEO of OpenStore, which acquires small direct-to-consumer businesses. Keith co-founded Opendoor and led the first institutional investments in DoorDash and Affirm. He has early stakes in YouTube, Palantir, Lyft, Airbnb, Eventbrite, and Wish, and also led investments in Faire, Ramp, Trade Republic, and Stripe. He’s regarded as one of the greatest early stage investors.

Bradley Tusk is a venture capitalist, political strategist, philanthropist and writer. He is the CEO and co-founder of Tusk Ventures, the world’s first venture capital fund that invests solely in early stage startups in highly regulated industries, and the founder of political consulting firm Tusk Strategies. Bradley’s family foundation is funding and leading the national campaign to bring mobile voting to all U.S. elections. Tusk Philanthropies also runs and funds anti-hunger campaigns that have led to the creation of anti-hunger policies and programs (including universal school breakfast programs) in 22 different states, helping to feed over 12.5 million people. Bradley is the author of The Fixer: My Adventures Saving Startups From Death by Politics and Obvious in Hindsight (coming out this November), writes a column for Fast Company, hosts a podcast called Firewall about the intersection of tech and politics, and is the co-founder of the Gotham Book Prize. He recently opened a bookstore, podcast studio, event space and cafe called P&T Knitwear on Manhattan's lower east side. He is also an adjunct professor at Columbia Business School.

0:00 - Intro

2:03 - The Incentives of Politics

10:57 - Bradley’s Philosophy

18:33 - More Political Parties and Fixing Political Polarization

25:13 - Big Tech Antitrust

29:09 - What Bradley Would Change

32:23 - The Decline of Trust in Institutions 

36:12 - Tusk Ventures

37:53 - Requests for Startups

39:50 - Debt, Inflation, and COVID

46:31 - The Story of Uber 

49:29 - How Uber Beats Lyft

52:59 - Weaponizing a Constituency 

54:53 - Regulated Industries Bradley’s Excited About 

57:54 - Crypto

1:01:40 - Psychedelics and Doing Ketamine 

1:07:21 - What Keeps Bradley Up at Night?

1:10:48 - Mobile Voting 

1:15:41 - Doing Lots of Things at Once

1:18:25 - Why Credentials Are Overrated

1:23:42 - On Happiness

1:28:31 - What Should More People Be Thinking About?

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