Lagrange Point

What kicked off early life on earth? Organic chemistry and early life need the right minerals to be present and accessible. What helped unlock early minerals on earth like phosphorous to kick start life? Lightning strikes seem rare, but they're much more frequent than meteorites. Early life on Earth could have been helped along through lightning strikes and meteorites. DNA, RNA and Proteins are locked in a complex dance, but which came first. DNA can't replicate without the help of protein and RNA, so how did we develop DNA in the first place? Is it possible for RNA to replicate on it's own?

1. Benjamin L. Hess, Sandra Piazolo, Jason Harvey. Lightning strikes as a major facilitator of prebiotic phosphorus reduction on early Earth. Nature Communications, 2021; 12 (1) DOI: 10.1038/s41467-021-21849-2

How does RNA work to protect your brain and keep it safe after a traumatic event? Micro RNA can play an important role in healthy brain development. Without key micro RNA, the development of the brain can run out of control. Without key microRNA, your can develop neurodevelopmental disorders. Without oxygen your neurons starve, so how can you protect them?  How can you use mRNA to make neurons more resilient and recover after a lack of oxygen? Getting proteins across the blood brain barrier is tricky, so can they be snuck in via mRNA? Using mRNA, you can produce proteins to add brain recovery right where they're needed most.

1. Vijay Swahari, Ayumi Nakamura, Emilie Hollville, Hume Stroud, Jeremy M. Simon, Travis S. Ptacek, Matthew V. Beck, Cornelius Flowers, Jiami Guo, Charlotte Plestant, Jie Liang, C. Lisa Kurtz, Matt Kanke, Scott M. Hammond, You-Wen He, E.S. Anton, Praveen Sethupathy, Sheryl S. Moy, Michael E. Greenberg, Mohanish Deshmukh. MicroRNA-29 is an essential regulator of brain maturation through regulation of CH methylation. Cell Reports, 2021; 35 (1): 108946 DOI: 10.1016/j.celrep.2021.108946

Hydrogen fuel promises a cleaner future, but the methods to make it are often dirty. A new approach recycles and treats waste water with sunlight to efficiently produce hydrogen. A new electrolysis approach turns waste antibiotics into hydrogen fuel cells. Removing antibiotics and other pharmaceuticals from waster water can be tricky, but a new technique turns that into green energy. Aquaculture is growing rapidly, but it is leading to antimicrobial resistance? What contributes more to antimicrobial resistance - fish farms or waste water? Incorrectly managed waster water can lead to superbugs.

References:

1. Yaoyao Wu, Yuqiong Li, Hejing Hu, Guoshen Zeng, Chuanhao Li. Recovering Hydrogen Energy from Photocatalytic Treatment of Pharmaceutical-Contaminated Water Using Co3O4 Modified {001}/{101}-TiO2 Nanosheets. ACS ES&T Engineering, 2021; 1 (3): 603 DOI: 10.1021/acsestengg.1c00003

Can you find fresh water in the middle of the ocean? What happens when a geyser of fresh water erupts from the sea floor into the ocean? A sudden freshwater spring can radically change the ocean floor. How do plankton shells and coral help us monitor a changing climate? Life in the oceans can help sequester carbon. We can track the way the climate has changed in the past by studying strontium isotopes in seawater. Changing climates can impact life in shallow and deep water, which can lead to changes in the carbon cycle. Tiny creatures like copepods can have a huge impact on our ocean food web. How do tiny creatures like copepods gather in ephemeral ocean zephyrs. Tiny vortexs can act as a gathering place for tiny but important sea creatures.

1. Eric Attias, Steven Constable, Dallas Sherman, Khaira Ismail, Christopher Shuler, Henrietta Dulai. Marine Electromagnetic Imaging and Volumetric Estimation of Freshwater Plumes Offshore Hawai'i. Geophysical Research Letters, 2021; 48 (7) DOI: 10.1029/2020GL091249

Mars was once covered with water, so where did all the water on Mars go? What happened to the water in the Martian atmosphere? Why isn't there an abundance of heavy water in the Martian atmosphere? Water can get trapped inside rocks and minerals without volcanoes to cycle them. Volcanoes and tectonics help sequester, cycle and release water, so what happens on a planet without them? How can we hunt for signs of water atmospheres on exoplanets? On hot rocky exoplanets with oceans of magma, what happens to their hydrogen rich atmospheres?  An atmosphere of of hydrogen can slowly turn and change into water with the help of a magma ocean. 

1. E. L. Scheller, B. L. Ehlmann, Renyu Hu, D. J. Adams, Y. L. Yung. Long-term drying of Mars by sequestration of ocean-scale volumes of water in the crust. Science, 2021; eabc7717 DOI: 10.1126/science.abc7717

Space is hard, things are different there which means something simple as salmonella becomes much more challenging. The rules of bacterial infection and response change once you're in space. How does your body respond to bacterial infection in microgravity environments? Getting sick in space may be worse than on earth. The human microbiome is incredible diverse and not well understood. Your gut contains 100,000s of bacteria groups, virus and other things. A large global study of gut microbiome has revealed thousands of new virus and bacteria types.

1. Jennifer Barrila, Shameema F. Sarker, Nicole Hansmeier, Shanshan Yang, Kristina Buss, Natalia Briones, Jin Park, Richard R. Davis, Rebecca J. Forsyth, C. Mark Ott, Kevin Sato, Cristine Kosnik, Anthony Yang, Cheryl Shimoda, Nicole Rayl, Diana Ly, Aaron Landenberger, Stephanie D. Wilson, Naoko Yamazaki, Jason Steel, Camila Montano, Rolf U. Halden, Tom Cannon, Sarah L. Castro-Wallace, Cheryl A. Nickerson. Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium. npj Microgravity, 2021; 7 (1) DOI: 10.1038/s41526-021-00136-w

Squid can change colours, reflect light and blend in with their surroundings. How does the changing colours on squid skin work? What proteins and structures enable squid skin to reflect and amplify varying light? Squid can blend themselves into the starlight with the aid of bio-luminescence. The symbiotic relationship between bacteria and squid starts right after birth, and helps them shine to avoid predators and catch prey. A baby squid may not start out bioluminescent but a rapid spread of the right bacteria turns on the lights.

1. Katherine E. Zink, Denise A. Ludvik, Phillip R. Lazzara, Terry W. Moore, Mark J. Mandel, Laura M. Sanchez. A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ. mBio, 2021; 12 (2) DOI: 10.1128/mBio.03637-20

We find out about the outreach and impact of March Mammal Madness. What happens when 65 animals face off for bragging rights? Find out in #2021MMM . By sharing science with a dramatic flair, #2021MMM has brought attention to 1000s of scientific papers. From 1% of US High school classrooms, to a global audience of young and old, #2021MMM shows how science does not have to be boring. How do bats tune out the background noise and hunt tiny prey? Using acoustic tunnel vision, bats are able to hone in on their tiny prey. By echoing quietly, bats can detect the smallest of bugs.

1. Hinde, K., Amorim, C. E., Brokaw, A. F., Burt, N., Casillas, M. C., Chen, A., . . . Anderson, C. N. (2021). March mammal madness and the power of narrative in science outreach. ELife, 10. doi:10.7554/elife.65066

Slime with memories, and 3d printed materials to repair damaged neurons. How can a slime form memories? Where does it store them? What is the largest single cell organism and how does it remember things? How can you store memories in an interconnected series of tubes? How can you use 3D printed self assembling materials to help regrow damaged neurons?

1. Mirna Kramar, Karen Alim. Encoding memory in tube diameter hierarchy of living flow network. Proceedings of the National Academy of Sciences, 2021; 118 (10): e2007815118 DOI: 10.1073/pnas.2007815118

Perseverance has landed and begun it's long mission, but how can scientists on Earth help research on Mars? Can we study life on Mars here on Earth? Robotic missions aren't the only way Martian rock has made it's way to Earth. Rare meteorites from Mars can be used to test how life would grow in Martian soil. Just how old is the Jezero crater? Can you date a crater without doing detailed tests? How does measuring lunar craters help us put a date on the age of Martian craters like Jezero?

1. T. Milojevic, M. Albu, D. Kölbl, G. Kothleitner, R. Bruner, M. Morgan. Chemolithotrophy on the Noachian Martian breccia NWA 7034 via experimental microbial biotransformation. Communications Earth & Environment, 2021 DOI: 10.1038/s43247-021-00105-x