In this episode of Leading Minds Revealed, host Michael Apollo sits down with Mo Jamous, Chief Information Officer at U.S. Bank, for a deeply human conversation on leadership, purpose, and AI-driven transformation.
Mo shares how purpose becomes an anchor during uncertainty, why technology should be used to empower—not replace—people, and how leaders can stay grounded while navigating rapid, overlapping waves of change. Drawing from decades of experience across digital, cloud, and AI transformations, Mo offers practical insight into building customer-obsessed cultures, introducing AI responsibly, and leading with clarity in moments of disruption.
This episode is a powerful exploration of future-ready leadership, human-centered technology, and the mindset required to create lasting impact in an AI-driven world.
Guest: Mo Jamous, Chief Information Officer, U.S. Bank
00:00 – Welcome to Leading Minds Revealed
00:55 – Episode focus: leading with purpose in transformation
01:37 – Introducing Mo Jamous, CIO of U.S. Bank
02:27 – Why purpose matters most during uncertainty
03:28 – Mo’s early story and discovering his leadership “why”
05:40 – Purpose as the constant through transformation
07:25 – Translating mission into daily leadership behaviors
08:35 – Staying grounded through customer feedback
09:16 – Turning personal habits into organizational culture
10:38 – What customer obsession looks like in practice
12:04 – Avoiding “shiny object” syndrome in AI
13:44 – Being intentional with innovation
15:22 – AI as empowerment, not replacement
17:54 – Addressing fear and misinformation around AI
19:19 – Creating value vs. cutting costs with AI
21:21 – Separating hype from reality in AI narratives
23:08 – Task-based work and human-AI collaboration
24:19 – Leadership principles that stay constant
26:40 – Psychological safety, collaboration, and trust
28:58 – Is AI fundamentally different from past tech waves?
30:39 – Why AI adoption lags behind capability
33:00 – Upskilling teams and AI literacy challenges
35:53 – Helping teams change how they work
38:22 – Progressive AI rollout strategies
40:32 – Human-centered change leadership
41:22 – Being present as a leader during uncertainty
43:28 – Recognition, visibility, and employee motivation
45:57 – How service shaped Mo’s leadership philosophy
48:38 – Is digital transformation really human transformation?
49:06 – Advice for leaders navigating AI-driven change
52:35 – Where to follow Mo Jamous
54:20 – Final reflections and closing
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