Reading his great-grandfather's memoir, Joe Dunthorne discovers a disturbing confession

In her early twenties Carol Cairns, the daughter of a priest in Ireland, had a passionate affair with a young bohemian poet called Benedict Ryan. In the Dublin of the 1960s, their improbable partnership burned bright but briefly. Somehow the gap in their backgrounds was too great. Not long after, life took her in a completely different direction. Shortly after her 70th birthday, while thinking of names for a grandson to be, she remembered Benedict. Where was he now? After a failed marriage, she used Skype to see if the flame still burned.

Carol tells Dr Sian Williams about the emotional moment they reunited, after almost half a century.

Producer; Tom Alban

Phillip Browne was born into a large and loving Windrush generation family in Birmingham. Church and singing were an important part of his upbringing, and when he struggled at school it was singing that gave him an escape and a status. But just as he was beginning to show signs of real potential, a devastating ear infection robbed him of his hearing completely in one ear - and Phillip was told by a doctor that a singing career was out of the question. Phillip's struggle in the aftermath of his illness and his need to find a job resulted in him becoming a London bus driver. He knew the security of employment was a relief to his father who had spent a lifetime working on the railways, but it seemed to be leading him further and further away from his dream. Until a chance meeting with an old college friend turned his life in an extraordinary new direction.

Phillip tells Dr Sian Williams about that Life Changing moment - and his incredible journey to the bright lights of the West End stage.

Producer: Tom Alban

Robin Elsey Webb is a young and already very successful yachtsman with a dream of tackling the famous Vendee Globe, the single-handed round the world yacht race. But his plans were shattered during a trip to Antigua, when he was violently attacked and suffered severe head injuries. With his life hanging in the balance, it fell to his partner Liz to make swift and bold decisions about his treatment. Robin's job was to try and stay alive.

Robin and Liz join Dr Sian Williams to piece together their own very different experiences of that terrifying ordeal, which changed so many things for both of them.

Producer: Tom Alban

As a bright adventurous 16 year-old, Angela Tilley was thrilled to get a job in a busy London office. But after a year's unwanted attention from one of her co-workers, attention that today we would call stalking, she started having panic attacks on the way to work. The attacks became a debilitating daily occurrence, leaving her mentally and physically exhausted. Her courage in pushing back against her fears, forging a career and having a family came at a huge personal cost. But one seemingly innocuous purchase was about to change her life forever.

Angela tells Dr Sian Williams about how she overcame her challenges and how she managed to stop her phobia defining her life.

Husband and father, Larry O’Brien, loved the freedom his job as a long-distance lorry driver gave him. But on March 6th 1987, that freedom was almost lost in the horror of the Zeebrugge ferry disaster, in which almost 200 people lost their lives. Larry – who could not swim – risked his own life to pull 30 people to safety.

When 18-year-old Stacey Goodwin got a job at a bookies, she put a pound coin into a slot machine and won enough money for a night out with her pals. It was the trigger for a destructive gambling addiction that led to a life of shame, brutal isolation and deceit. The money she lost over an eight-year period was eye-watering – on one occasion, frittering away a £50,000 online win in a matter of days. Sometimes suicidal, and always lonely, it was the damage she did to those closest to her which hurt the most.

When her addiction saw her undermine the financial security of someone she loved, she reached a crossroads. Stacey tells Dr Sian Williams how she found the strength to ask for help - and turned her life around.

Producer: Tom Alban

Warning: This episode contains discussions around suicide. Details of help and support are available through the BBC Action Line at bbc.co.uk/actionline.

In 1977, Ed Stewart was a happy-go-lucky teenager with his whole life ahead of him. With a new engineering job, a girlfriend and a motorbike, life was good. But when he dropped in on a friend’s party, a violent row with another teenager - who was carrying a shotgun - turned Ed’s whole life on its head.

Ed had to learn to navigate the world in an entirely different way, but he made a success of it - becoming a piano tuner to the stars and counting Jools Holland and Brian Ferry as his customers. Despite a life of adversity, he tells Dr Sian Williams how not just one, but two Life Changing moments led him to be what he refers to as a “glass-three-quarters-full” kind of bloke.

Producer: Tom Alban

For Lisa Hover and her husband Andy, life on the Hampshire Dorset border with their family of four children seemed idyllic. Even when a routine sight test on their young daughter Annabelle picked up an abnormality, it all seemed manageable. But the abnormality turned out to be early sight loss, which itself masked a more severe and life shortening genetic condition. With no cure available, Annabelle was determined the most from her limited life span.

Lisa talks to Dr Sian Williams about the challenges, joys and sadness she experienced - and Annabelle's dream to have a white Christmas with all the family.

Producer: Tom Alban

As a young man, Mohammed, AKA MFA Zaman, arrived in Britain from Bangladesh with a working visa, a patron and a job lined up as a chef. On arrival though, the promises of a bright future turned to ashes when he became a victim of modern slavery. But at this lowest of low ebbs in his life, Mohammed decided that he needed to do something - and that something was to volunteer at an old people's community club in Lewisham, near where he was living.

Mohammed tells Dr Sian Williams how this life-changing decision helped him to find freedom.

Producer: Tom Alban