Michael Irwin (University of California, Los Angeles, USA) discusses a Review concerning potential links of sleep disturbance and possible increased risk of Alzheimer's disease dementia.

Lindsay Wallace and Kenneth Rockwood join The Lancet Neurology to talk about their work on the association between frailty and the onset of Alzheimer's disease.

In the latest podcast from The Lancet Neurology, Jan Scheitz discusses the development of stroke–heart syndrome.

Mark Cook and Phillippa Karoly join The Lancet Neurology to discuss their retrospective study of cyclical patterns in epileptic seizures.

Bruce Trapp and Daniel Ontaneda discuss their retrospective study investigating cortical neuronal loss and cerebral white-matter demyelination in mulitple sclerosis.

Josep Dalmau joins The Lancet Neurology to discuss recognition and outcomes of autoimmune encephalitis after herpes simplex encephalitis.

David Eidelberg and Katharina Schindelbeck join The Lancet Neurology to explain their new review of the applications of network imaging biomarkers in Parkinson's disease.

Eugene Major and David Clifford join The Lancet Neurology to discuss their review of pathogenesis and treatments for progressive multifocal leukoencephalopathy.

Torbjörn Tomson discusses the issue of antiepileptic drugs during pregnancy and the risk of major congenital malformations.

Christian Elger discusses the diagnostic challenges in epilepsy with the detection and reporting of seizures.