In this podcast, we explore Crohn's disease: who it affects, what it is, how it works in the body, and what you can do about it. We relate the disease to screens on windows, which can degrade over time, letting unwanted bugs in the house. Tune in for the who, how, and what can be done about Crohn's!

References:

Roda, G., Chien Ng, S., Kotze, P. G., Argollo, M., Panaccione, R., Spinelli, A., ... & Danese, S. (2020). Crohn’s disease. Nature reviews Disease primers, 6(1), 22. https://doi.org/10.1038/s41572-020-0156-2

Peyrin-Biroulet, L., Loftus, E. V., Colombel, J. F., & Sandborn, W. J. (2011). Long-term complications, extraintestinal manifestations, and mortality in adult Crohn's disease in population-based cohorts. Inflammatory bowel diseases, 17(1), 471-478. https://academic.oup.com/ibdjournal/article-abstract/17/1/471/4631202

Torres, J., Mehandru, S., Colombel, J. F., & Peyrin-Biroulet, L. (2017). Crohn's disease. The Lancet, 389(10080), 1741-1755. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)31711-1/abstract

Piovani, D., Danese, S., Peyrin-Biroulet, L., Nikolopoulos, G. K., Lytras, T., & Bonovas, S. (2019). Environmental risk factors for inflammatory bowel diseases: an umbrella review of meta-analyses. Gastroenterology, 157(3), 647-659. https://www.gastrojournal.org/article/S0016-5085(19)36709-5/fulltext

Marks, D. J., Rahman, F. Z., Sewell, G. W., & Segal, A. W. (2010). Crohn’s disease: an immune deficiency state. Clinical reviews in allergy & immunology, 38(1), 20-31. https://link.springer.com/article/10.1007/s12016-009-8133-2

Colombel, J. F., Panaccione, R., Bossuyt, P., Lukas, M., Baert, F., Vaňásek, T., ... & D'Haens, G. (2017). Effect of tight control management on Crohn's disease (CALM): a multicentre, randomised, controlled phase 3 trial. The Lancet, 390(10114), 2779-2789. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)32641-7/abstract