With Britain preparing to leave the European Union, countless trade agreements will have to be renegotiated - not just treaties between Britain and the EU, but also between Britain and the United States, among many others.

The Antonov An-225 is the world's biggest airplane, bar none. And only one was ever built. This colossus is designed to carry other giants, such as a turbine, weighing as much as 117 compact cars, from Prague in the Czech Republic to a refinery in Perth, Australia. MADE IN GERMANY tags along on a logistical adventure.

A talk with Josef Janning of the European Council on Foreign Relations about how the Brexit vote is affecting international centers of commerce such as Dublin, Paris and Frankfurt.

Observers predict London’s status as a global commerce and financial center will take a hit. Many of its companies and banks have already announced plans to relocate to the EU. What changes can we expect?

The Brexit vote left British companies in a quandary. Many are even thinking about relocating out of Britain. Unions are also facing a dilemma. Britain's withdrawal from the European Union would affect some three million jobs dependent on exports.

Britain is the European Union's second largest economy. Now its people want to leave the EU. What consequences could Brexit have for Britain's population, its economy and for the EU? Who are the winners and losers?

Made in Germany talks to Michael Wolgemuth of Open Europe. Open Europe Berlin is an independent German think tank with pro-EU leanings.

We talk to Michael Wolgemuth of Open Europe. Open Europe Berlin is an independent German think tank with pro-EU leanings.

"It's a catastrophe for the German economy"! Companies fear massive damage - most especially, the nearly 2500 German firms that manufacture in Britain. German exporters have to brace for major losses in revenues.

Britain is the European Union's second largest economy. Now its people want to leave the EU. What consequences could Brexit have for Britain's population, its economy and for the EU? Who are the winners and losers?

Could Brexit trigger a domino effect among EU members? There are many factions in the Czech Republic, for instance, who've long wanted to see their country leave the EU - even though the country benefits from Europe’s open borders and EU subsidies.