When a vicious storm breaks out in the Nevada desert, 10 people seek refuge in an isolated motel. At the same time, a serial killer (Pruitt Taylor Vince) under the care of psychiatrist Doctor Mallick (Alfred Molina) -- who has just found the killer's revealing journal -- awaits execution for murdering a group of motel guests. When the storm-stranded travelers realize they are being killed off one by one, limo driver Ed Dakota (John Cusack) bids to stay alive and reveal the murderer's identity.

When his abducted brother returns, seemingly a different man with no memory of the past 19 days, Jin-seok chases after the truth behind the mysterious kidnapping.