Seth Shostak from the Search for Extraterrestrial Intelligence presents SETI's scientific approach to detecting signals from extraterrestrial civilizations while addressing the challenges and prospects for making contact with alien intelligence. His work with radio telescopes and signal analysis provides authoritative perspective on humanity's systematic efforts to discover evidence of extraterrestrial technology and communication. Shostak discusses the methodology used to distinguish artificial signals from natural radio phenomena while examining how SETI research has evolved to address broader possibilities for extraterrestrial contact detection. He addresses the famous "Wow!" signal and other intriguing detections that have generated excitement within the SETI community while ultimately proving inconclusive for confirming extraterrestrial origin. The conversation covers the assumptions underlying SETI research, including expectations about how advanced civilizations might communicate and the likelihood that they would use radio technology detectable by human equipment. Shostak examines the implications of SETI success for human society while exploring how first contact through radio signals might differ from the direct physical contact reported in UFO encounters. His presentation addresses the relationship between SETI research and UFO phenomena, examining why mainstream science embraces radio searches while often dismissing reports of actual alien visitation. The discussion explores the statistical probabilities for extraterrestrial intelligence and the timeline for possible SETI success while examining how such discoveries might transform human understanding of our place in the cosmic community. Shostak's work demonstrates how systematic scientific search complements other approaches to investigating extraterrestrial intelligence.