The broadcast opens with the ongoing controversy surrounding Kathleen Keating's identification of the Antichrist, generating massive response and website traffic difficulties. An extraordinary email arrives from someone claiming to be the actual Antichrist, offering detailed theological corrections and mocking Keating's research methodology. This sets the stage for Brian Alexander from Wired Magazine discussing the rapidly advancing frontier of human cloning technology and its ethical implications. Open lines segments feature callers weighing in on the Antichrist controversy, with Keating herself appearing to address the unprecedented reaction to her revelations. The program balances cutting-edge science reporting on cloning with esoteric speculation about biblical prophecy, demonstrating the show's willingness to explore both technological futures and apocalyptic possibilities in equal measure.