MDS PODCAST: Defining Parkinson's disease

Dr. Mitra Afshari discusses with Dr. Jeffrey Hausdorff the potential of AI-enabled digital biomarkers in Parkinson’s disease, including their role in patient monitoring, challenges in accuracy and reliability, and barriers to clinical implementation.

Ms. Nicole Duff discusses with Dr. Sara Lidstone the diagnosis and management of functional neurological and movement disorders, including clinical signs, patient-centered communication, and the importance of interdisciplinary rehabilitation.

Dr. Mitra Afshari discusses with Dr. Raul Martínez-Fernández recent advances in MRI-guided focused ultrasound for essential tremor and Parkinson’s disease, including improvements in safety and efficacy, its relationship with deep brain stimulation, and emerging neuromodulation approaches.

Dr. Eduardo de Pablo-Fernández discusses with Dr. Samuel Kim recent advances in Huntington’s disease, including genetic mechanisms, emerging biomarkers, and the potential of huntingtin-lowering therapies and gene therapy.

Dr. Eduardo de Pablo-Fernández discusses with Prof. Tom Foltynie emerging disease-modifying and restorative treatments for Parkinson’s disease, including recent clinical trial findings and promising therapeutic approaches.

Ms. Nicole Duff discusses with Dr. Alison Yarnall the prevalence and impact of frailty in Parkinsonism, including how it is identified and measured and its implications for clinical trials and patient care.

Dr. Jerome Honnorat sits down with host Dr. Divyani Garg at the 2026 MDS international Congress to review the most recent advancements in autoimmune movement disorders.

Dr. Sabine Hilfiker addresses with Dr. Tiago Outeiro the slight differences of alpha-synuclein pathology in LRRK PD and what they could mean in terms of cell biology and molecular mechanisms.

Dr. Ignacio Mata discusses with Dr. Divyani Garg the dramatic increases in genetic testing globally over the last several years that have enhanced our understanding of the genetic architecture of Parkinson’s disease.

Prof. Wassilios Meissner discusses scientific advances in multiple system atrophy,  from our growing understanding of MSA pathophysiology to potential diagnostic biomarkers to investigational therapeutics.