MedEdTalks - Rheumatology

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome, is a rare form of vasculitis that primarily affects the small blood vessels. Individuals diagnosed with EGPA commonly have a history of asthma and/or allergies. Inflammation associated with EGPA can lead to injury in multiple organ systems, including the sinuses, lungs, gastrointestinal system, heart, and kidneys. Early diagnosis and treatment are critical when managing EGPA to improve patient outcomes and reduce symptom burden. Education is needed to provide clinicians with the latest information regarding optimal diagnostic and management strategies, including newer steroid-sparing therapy options. In this CME podcast series, experts will provide guidance on differentiating EGPA from related vasculitides or eosinophilic conditions, highlight recent clinical data, and discuss therapeutic advancements.

Transcript available here: https://tinyurl.com/EGPA1

In this case-based podcast, Leonard H. Calabrese, DO, and Adam Brown, MD, discuss a patient who presents to the hospital with fever of unknown origin.

In this case-based podcast, Leonard H. Calabrese, DO, and Adam Brown, MD, discuss a patient presenting for a second opinion for GCA after initial workup and treatment by her primary care physician.

In this case-based podcast, Leonard H. Calabrese, DO, and Ann P. Murchison, MD, MPH, discuss issues related to the workup, diagnosis, and treatment of a patient with new-onset visual symptoms presenting to the emergency department.

In this case-based podcast, Leonard H. Calabrese, DO, and Sebastian Unizony, MD, discuss issues related to the workup, diagnosis, and treatment of a patient with complicated GCA.

In this case-based podcast, Leonard H. Calabrese, DO, and Sebastian Unizony, MD, discuss issues related to the workup, diagnosis, and treatment of a patient with uncomplicated, or "classic", GCA.

Giant cell arteritis (GCA) is the most common form of medium- and large-vessel vasculitis. Despite new treatment options for patients with GCA, delays in diagnosis and treatment lead to poor outcomes, such as the increased risk for visual impairments and incidence of heart attacks, transient ischemic attacks, and/or mortality. Diagnosis of GCA remains difficult due to the nonspecific nature of many early symptoms. Until recently, therapeutic options were limited to prolonged, high-dose glucocorticoid therapy, which has the potential for many undesirable side effects. In this Curbside Consults series, expert faculty will discuss clinical cases that emphasize appropriate medical work-up for timely identification of GCA and early intervention strategies, as well as provide guidance for implementing evidence-based glucocorticoid-sparing therapy. Experts will also discuss the importance of a multidisciplinary approach to optimize the work-up and care of patients with GCA.

This educational activity will discuss management strategies for ANCA-associated vasculitis, focusing on GPA and MPA.

This educational activity will provide insight into making an accurate and timely diagnosis of ANCA-associated vasculitis.

This educational activity will discuss treatment strategies for patients with pemphigus vulgaris.