While VKA-related GI bleeds are common, clinicians need to be aware of the severity of the bleed, especially in cases of hemodynamic instability. To get a better understanding of the impact of this severity, Dr. Majed Refaai from the University of Rochester Medical Center shares insights on these life-threatening bleeds.

Learn more about the efficacy and other clinical data for this preventive migraine treatment option. Dr. Brad Torphy highlights clinical data on this treatment option.

For patients with chronic or episodic migraine, what treatment options should we consider? To help answer that question, Dr. Wade Cooper discusses a treatment option for migraine.

Because Sjogren's disease has no calculable disease activity scores or established guidelines, how do clinicians monitor disease activity?

Dr. Ethan Craig is joined by Dr. Sara S. McCoy, MD, PhD who runs the Sjögren’s Clinic at the University of Wisconsin to discuss activity monitoring for Sjögren’s disease.

Dr. Craig and Dr. McCoy are Novartis consultants.

247548 11/22

Lung cancer incidence is decreasing due in part to reduced smoking rates, and new trends are emerging as things change. But despite these advancements, some challenges remain to be solved. Explore those challenges and key strategies for overcoming them in this four-part series.

PP-US-8201a-1697 07/23

Is now the time to shift the asthma management paradigm to prioritize remission as our goal? Dr. Charles Turck is joined by Professor Andrew Menzies-Gow, Director of the Lung Division and Deputy Medical Director at the Royal Brompton and Harefield Hospitals, London, UK, to discuss remission as a goal for patients with asthma. Together, they review a recently published expert consensus framework for asthma remission and discuss whether targeting remission could lead to better outcomes for patients.

At the time of recording, Professor Menzies-Gow provided services to AstraZeneca as an External Expert; Professor Menzies-Gow is now a permanent employee at AstraZeneca.

©2022 Amgen and AstraZeneca. All rights reserved. US-69837 Last Updated 12/22

Different domains of psoriatic arthritis can look different in each of our patients. How should that factor into our evaluation and treatment approach for this disease? Dr. Jason Liebowitz sits down with Dr. Laura Coates, an Associate Professor at Oxford University, to explore a domain-based approach to care.

Dr. Liebowitz and Dr. Coates are Novartis consultants.

Can multi-cancer early detection (MCED) tests potentially lead to a reduction in the number of people who die from the disease by improving screening rates and extending screening for cancers without standard screening today? So what do we need to know about these tests? To discuss this more in-depth, Dr. Charles Turck is joined by Dr. Tomasz Beer, Chief Medical Officer for Multi-Cancer Early Detection at Exact Sciences Corporation and Adjunct Professor of Medicine at the OHSU Knight Cancer Institute.

© 2022 Exact Sciences Corporation. All rights reserved.
US.CAG.00020.HCP 12/22

It’s important to recognize that older adults are more susceptible to influenza infection—as well as increased severity of infection—than younger, healthier populations.1 Fortunately, there are vaccines available that can help prevent influenza in this aging population. But do the relative benefits and harms of higher-dose and adjuvanted vaccines, compared with one another and with other influenza vaccines, favor the use of any one or more of these vaccines over other age-appropriate options for people 65 and older?2 That's the exact question the CDC’s Advisory Committee on Immunization Practices (ACIP) sought to answer and what Dr. Charles Turck discusses with Dr. Paul Hunter, Associate Professor in the Department of Family Medicine and Community Health at the University of Wisconsin School of Medicine and Public Health.

References:
1. Centers for Disease Control and Prevention. Fly & People 65 Years and Older. Accessed August 16, 2022. https://www.cdc.gov/flu/highrisk/65over.htm.
2. National Center for Immunization & Respiratory Diseases. Advisory Committee on Influenza Practices. Influenza Vaccines for Older Adults: GRADE Summary. Accessed August 16, 2022.

USA-FLUD-22-0056 December 2022

To help us understand how axial spondyloarthritis (axSpA) and inflammatory back pain (IBP) differ, Dr. Ethan Craig is joined by Dr. Lianne Gensler from the UCSF Spondylitis Clinic at the University of California San Francisco Medical Center.

Dr. Craig and Dr. Gensler are Novartis consultants.

249165 11/22