Spinal muscular atrophy (SMA) is a challenging rare disease that requires a diagnosis and access to treatment as early as possible. To help us understand the importance of early treatment, Dr. Sandra Reyna from Novartis Gene Therapies shares key considerations for optimizing outcomes and gives us some insight into available SMA treatment options, focusing on the gene therapy ZOLGENSMA.

© 2022 Novartis Gene Therapies, Inc.
US-ZOL-22-0129 08/22

As we age, our immune system becomes weaker and is therefore unable to ward off infection as easily as in our younger years.1 This is particularly troublesome during flu season. In fact, the CDC’s Advisory Committee on Immunization Practices (ACIP) recently looked at flu vaccine data for adults aged 65 years and older, and they now recommend that this age group preferentially receive higher dose or adjuvanted vaccines over standard dose unadjuvanted vaccines when available.2 So what was the data that led to these updated recommendations? Joining Dr. Matt Birnholz to share those key findings and the role of adjuvanted vaccines like FLUAD® QUADRIVALENT (Influenza Vaccine, Adjuvanted) in preventing influenza in older adults is Dr. David Canaday, Professor in the Division of Infectious Diseases & HIV Medicine at Case Western Reserve University in Cleveland.

Avoid use in patients who have experienced any severe allergic reactions to any component of the vaccine. For more risk information please see below or consult the Full US Prescribing Information for FLUAD® QUADRIVALENT here.

References:
1. Gavazzi G, Krause KH. Ageing and infection. Lancet Infect Dis. 2002;2(11):659-666.
2. Centers for Disease Control and Prevention. Past seasons estimated influenza disease …

Declines in muscle strength and endurance are common as people get older, and there’s a need to identify effective interventions to help. Could Urolithin A, a nutritional supplement shown to improve cellular health, be a part of the solution? Dr. Anurag Singh, Chief Medical Officer at Amazentis, shares new clinical data on Urolithin A’s impact on muscle function among adults 65 years and older.

Age-related declines in muscle strength can begin as early as one’s thirties, and mitochondrial dysfunction is considered a contributing factor in this decline. A Urolithin A nutritional supplement supports mitochondrial health and may help improve muscle performance. Dr. Chris Rinsch, Chief Executive Officer and co-founder at Amazentis, shares clinical data on Urolithin A supplementation.

For patients with oligoarticular arthritis, how can imaging features help us distinguish psoriatic arthritis from other inflammatory processes? Joining Dr. Ethan Craig to answer that question is Dr. Alexis Ogdie-Beatty from the Perelman School of Medicine at the University of Pennsylvania.

Dr. Craig and Dr. Ogdie-Beatty are Novartis consultants.

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What does the therapeutic landscape look like for patients with giant cell arthritis (GCA)? Joining Dr. Anisha Dua to highlight the need for more targeted therapies is Dr. Mike Putman from the Medical College of Wisconsin.

Dr. Dua and Dr. Putman are Novartis consultants.

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Digital tools have emerged as one of the newest therapeutic modalities for behavior modification in several chronic psychiatric diseases,1 such as major depressive disorder, chronic insomnia, and substance use disorders. But what exactly are these digital tools, and what does their use look like in practice? Joining Dr. Jennifer Caudle to answer those and other key questions regarding the use of digital tools in psychiatry is Dr. Daniel Karlin, Assistant Professor of Psychiatry at Tufts University in Boston and Chief Medical Officer at MindMed in New York City.

References:

1. Patel NA, Butte AJ. Characteristics and challenges of the clinical pipeline of digital therapeutics. NPJ Digit Med. 2020;3:159.

Since the use of digital tools in psychiatry and mental health treatment is already a reality, it’s important to know how to find the digital tool that best suits your and your patients’ needs and—perhaps even more importantly—how to encourage patients to use the tool. That’s why Dr. Charles Turck speaks with Dr. Matthew Brams, who shares the benefits of digital tools, the data he’s able to gain from them, how he talks to patients, and more.

July 2022 US.UNB.X.22.00009

How does preclinical psoriatic arthritis (PsA) progress into chronic PsA? To dive into this path of progression, Dr. Ethan Craig is joined by Dr. Alexis Ogdie-Beatty from the Perelman School of Medicine at the University of Pennsylvania.

Dr. Craig and Dr. Ogdie-Beatty are Novartis consultants.

221663 7/22

What are some imaging factors we should consider when monitoring giant cell arthritis (GCA) and the medication prescribed for it? Dr. Anisha Dua is joined by Dr. Mike Putman to explore these factors.

Dr. Dua and Dr. Putman are Novartis consultants.

199849 6/22