Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Anjay Rastogi, MD, PhD

Defined as high potassium levels in the blood, hyperkalemia can be a life-threatening condition.1 Hyperkalemia is often associated with chronic kidney disease and can be silent or present itself with non-specific symptoms.1,2 However, there are challenges in managing hyperkalemia as a recurrent event.1,3 To help address these challenges, Dr Charles Turck discusses with Dr Anjay Rastogi, nephrologist and head of the CORE Kidney Program at UCLA, the burden of hyperkalemia and how potassium binders can help manage it.3,4

©2022 AstraZeneca. All rights reserved. US-57356 Last Updated 2/22

Host: Jacqueline Nicholas, MD, MPH

Ever had a multiple sclerosis (MS) patient who needed to start a DMT? Listen to Dr. Jacqueline Nicholas, System Chief of Neuroimmunology and Director of MS Research at Ohio Health, and Kim, a patient who has been living with MS for seven years, share their experiences with the treatment decision process, including benefit-risk considerations, treatment goals, and patient preferences. They talk about the process for starting and continuing treatment with TYSABRI® (natalizumab) and how Biogen Support Services can help.

Please see Important Safety Information, including Boxed Warning for PML, below.

Host: Thomas Oppelt, PharmD, BCPS

Guest: Raj Dasgupta, MD, FACP, FCCP, FAASM

COVID-19 is still an ongoing public health threat, and the continual emergence of concerning variants has resulted in ongoing hospitalizations. Joining us to review VEKLURY, the first and only FDA-approved treatment for COVID-19 in hospitalized patients, its antiviral mechanism of action, and efficacy and safety results from the ACTT-1 clinical trial, is frontline COVID-19 treater Dr Raj Dasgupta.

Dr Raj Dasgupta is a quadruple board-certified pulmonary and critical care specialist at one of the largest hospitals in Los Angeles, California. He will be joined by Tom Oppelt, Senior Director of Medical Affairs at Gilead Sciences.

Host: Jane Mast, PA-C, MPAS, DMSc

Guest: Douglas DiRuggiero, DMSc, PA-C

Join podcast guest Doug DiRuggiero, PA, a certified physician assistant and the founding president of Georgia Dermatology Physician Assistant Society, and host Jane Mast, a Novartis Medical Director and certified physician assistant in a discussion focusing on the diagnosis and management of psoriasis in pediatric and adolescent patients.

During their discussion, they address the following topics:

• Important clinical features of psoriasis in children and adolescents and how they may differ from those in adult patients
• Communication strategies to use when talking to parents about their child’s psoriasis
• Psychosocial impact of psoriasis
• Approaches to management

This podcast is sponsored by Novartis Pharmaceuticals Corporation and the podcast guest is being compensated for his time.

© 2021 Novartis Pharmaceuticals Corporation
171857 12/21

Guest: Eser Adiguzel, PhD (Novartis)

Guest: Randy Wong, MD (Novartis)

A common complication of diabetes is diabetic macular edema (DME). Of the 463 million people worldwide aged 29 to 79 years old living with diabetes, many will develop diabetic retinopathy at about a rate of 27 percent. And of those 27 percent, a smaller subset will develop DME.1,2 Given its high prevalence, it’s important to understand its pathophysiology, clinical features, challenges, and management approaches, which is why Drs. Eser Adiguzel and Randy Wong are here to share their insights on DME.

1. International Diabetes Federation. Diabetes Atlas 9th Edition. 2019.
2. Thomas RL, et al. Diabetes Res Clin Pract. 2019 Nov; 157:107840.

181534 2/22

Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Diane M. Harper, MD, MPH, MS

While HPV 16 causes nearly 60 percent of the cervical cancers, it’s only associated with about 20 percent of the NILM, ASCUS, and LSIL cytology diagnoses. This means that 80 percent of early screening abnormalities associated with types other than 16 are missed. So how can we better detect types beyond HPV types 16 and 18? Joining Dr. Charles Turck to discuss same-genotype persistence for high-risk HPV is Dr. Diane Harper.

Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Donald Middleton, MD

Influenza causes considerable morbidity and mortality in children. In fact, the CDC estimates that from the 2010-2011 season to the 2019-2020 season, seasonal flu-related hospitalizations among children younger than 5 years old have ranged from 7,000 to as high as 26,000 every year.1 This is a sobering reminder of the pivotal role vaccination plays in preventing influenza disease, and now, recent safety and immunogenicity data has led to the expanded age indication for the cell-based vaccine FLUCELVAX QUADRIVALENT. Explore that data and what this approval means for patients 6 months of age and older with Drs. Charles Turck and Donald Middleton.

1. Centers for Disease Control and Prevention. Flu and young children. https://www.cdc.gov/flu/highrisk/children.htm. Accessed December 22, 2021

USA-QIVc-21-0169 December 2021

Host: Matt Birnholz, MD

Guest: Andrew Wang, MD

Although hypertrophic cardiomyopathy is the most common inherited heart disease, it is estimated that many patients remain undiagnosed. But why is that, what are the steps to help close the diagnostic gap, and what are the current management approaches for HCM? Joining Dr. Matt Birnholz to answer these questions and more is Dr. Andrew Wang, Vice Chief for Clinical Affairs for Duke University's Division of Cardiology and Director of the Duke Hypertrophic Cardiomyopathy Clinic.

Guest: S. Michelle Shiller, DO, AP/CP, MGP

Guest: John V. Heymach, MD, PhD

Exon 20 insertion mutations account for up to 10 percent of EGFR mutations and approximately 2 percent of all non-small cell lung cancer mutations. Although less common, EGFR mutations at exon 20 have an important impact on therapy selection. That’s why Dr. John Heymach speaks with Dr. Michelle Shiller about what those impacts are as well as the available therapies for patients with these mutations.

All trademarks are the property of their respective owners.
©2021 Takeda Pharmaceuticals U.S.A., Inc. All rights reserved.
December, 2021. VV-MEDMAT-56973

Host: Linda Stein Gold, MD

Guest: Jonathan S. Weiss, MD

When assessing the burden of psoriasis, are you looking beyond the skin? Here to share their perspectives on the burden of psoriasis are Dr. Linda Stein Gold and Jonathan Weiss. Together, they’ll discuss the psychological impacts of psoriasis, how we can talk to patients, and more.