Join our scientific team in the discussion of the 3 most clinically impactful papers of the month, the crème de la crème of our weekly top picks.

This month we’re discussing:

#1 - Triple Versus Dual Lipid-Lowering Therapy in Acute Coronary Syndrome: The ES-BempeDACS Randomized Clinical TrialDOI: https://doi.org/10.1093/eurheartj/ehaf724

#2 - Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial

DOI: 10.1056/NEJMoa2509688

#3 - Eloralintide, a selective amylin receptor agonist for the treatment of obesity: a 48-week phase 2, multicentre, double-blind, randomised, placebo-controlled trial

DOI: 10.1016/S0140-6736(25)02155-5

Scientific team:Ricardo Ladeiras Lopes, Mário Santos and João Sérgio Neves

Discover Medical Portfolio App weekly top picks - the latest and most relevant papers, curated by our team of experts! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/medicalportfolioapp⁠⁠

Join our scientific team in the discussion of the 3 most clinically impactful papers of the month, the crème de la crème of our weekly top picks. This month we’re discussing:Left bundle branch area pacing vs right ventricular pacing in preserved or mildly reduced ejection fraction: the PACE-HF trialDOI: https://doi.org/10.1093/eurheartj/ehaf724Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trialDOI: https://doi.org/10.1016/S0140-6736(25)01375-3An AI-Powered Lifestyle Intervention vs Human Coaching in the Diabetes Prevention Program: A Randomized Clinical TrialDOI: https://doi.org/10.1001/jama.2025.19563Scientific team:Ricardo Ladeiras Lopes, Mário Santos and João Sérgio NevesDiscover Medical Portfolio App weekly top picks - the latest and most relevant papers, curated by our team of experts! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/medicalportfolioapp⁠⁠

Inspiring. Insightful. Pragmatical.The road to success and excellence is bumpy! We ask the experts for advice on how to tackle the roadblocks, master soft skills and become a leader!

Join our scientific team in the discussion of the 3 most clinically impactful papers of the month, the crème de la crème of our weekly top picks.This month we’re discussing:Vericiguat in patients with chronic heart failure and reduced ejection fraction (VICTOR): a double-blind, placebo-controlled, randomised, phase 3 trialDOI: https://doi.org/10.1016/S0140-6736(25)01665-4Increasing the Potassium Level in Patients at High Risk for Ventricular ArrhythmiasDOI: ⁠https://doi.org/⁠10.1056/NEJMoa2509542Comparison of an Energy-Reduced Mediterranean Diet and Physical Activity Versus an Ad Libitum Mediterranean Diet in the Prevention of Type 2 Diabetes: A Secondary Analysis of a Randomized Controlled TrialDOI: https://doi.org/10.7326/ANNALS-25-00388Scientific team:Ricardo Ladeiras Lopes, Mário Santos and João Sérgio NevesDiscover Medical Portfolio App weekly top picks - the latest and most relevant papers, curated by our team of experts! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/medicalportfolioapp⁠⁠

Inspiring. Insightful. Pragmatical.The road to success and excellence is bumpy! We ask the experts for advice on how to tackle the roadblocks, master soft skills and become a leader!

Join our scientific team in the discussion of the 3 most clinically impactful papers of the month, the crème de la crème of our weekly top picks.This month we’re discussing:Early Discontinuation of Aspirin after PCI in Low-Risk Acute Myocardial InfarctionDOI: https://doi.org/10.1056/NEJMoa2508808Digitoxin in Patients with Heart Failure and Reduced Ejection FractionDOI: https://doi.org/10.1056/NEJMoa2415471Efficacy and safety of single-anastomosis duodeno-ileal bypass with sleeve gastrectomy versus Roux-en-Y gastric bypass in France (SADISLEEVE): results of a randomised, open-label, superiority trial at 2 years of follow-upDOI: https://doi.org/10.1016/S0140-6736(25)01070-0Dapagliflozin in Patients Hospitalized for Heart Failure: Primary Results of the DAPA ACT HF-TIMI 68 Randomized Clinical Trial and Meta-Analysis of Sodium-Glucose Cotransporter-2 Inhibitors in Patients Hospitalized for Heart Failure

DOI: https://doi.org/10.1161/CIRCULATIONAHA.125.076575Scientific team:Ricardo Ladeiras Lopes, Mário Santos and João Sérgio NevesDiscover Medical Portfolio App weekly top picks - the latest and most relevant papers, curated by our team of experts! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/medicalportfolioapp⁠

Inspiring. Insightful. Pragmatical.The road to success and excellence is bumpy! We ask the experts for advice on how to tackle the roadblocks, master soft skills and become a leader!

Join our scientific team in the discussion of the 3 most clinically impactful papers of the month, the crème de la crème of our weekly top picks.This month we’re discussing:

Exploring safety of down-titrating diuretics in heart failure managementDOI: https://doi.org/10.1002/ejhf.3714

Artificial Intelligence–Enabled ECGs for Atrial Fibrillation Identification and Enhanced Oral Anticoagulant Adoption: A Pragmatic Randomized Clinical TrialDOI: https://doi.org/10.1161/JAHA.125.042106

Gradual Titration of Semaglutide Results in Better Treatment Adherence and Fewer Adverse Events: A Randomized Controlled Open-Label Pilot Study Examining a 16-Week Flexible Titration Regimen Versus Label-Recommended 8-Week Semaglutide Titration RegimenDOI: https://doi.org/10.2337/dc25-0690

Scientific team:Ricardo Ladeiras Lopes, Mário Santos and João Sérgio NevesDiscover Medical Portfolio App weekly top picks - the latest and most relevant papers, curated by our team of experts! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/medicalportfolioapp⁠

Inspiring. Insightful. Pragmatical.The road to success and excellence is bumpy! We ask the experts for advice on how to tackle the roadblocks, master soft skills and become a leader!

Join our scientific team in the discussion of the 3 most clinically impactful papers of the month, the crème de la crème of our weekly top picks.

This month we’re discussing:

Urgent surgery vs fibrinolytic therapy for left-sided prosthetic valve thrombosis: a randomized trialDOI: https://doi.org/10.1093/eurheartj/ehaf391

Structured Exercise after Adjuvant Chemotherapy for Colon CancerDOI: https://doi.org/10.1056/NEJMoa2502760

Add-On Treatment With Zilebesiran for Inadequately Controlled Hypertension: The KARDIA-2 Randomized Clinical TrialDOI: https://doi.org/10.1001/jama.2025.6681

Scientific team:Ricardo Ladeiras Lopes, Mário Santos and João Sérgio Neves

Discover Medical Portfolio App weekly top picks - the latest and most relevant papers, curated by our team of experts! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/medicalportfolioapp⁠