Semaglutide’s cardiovascular benefits extend beyond weight loss — it powerfully reduces visceral adipose tissue (VAT), the internal fat that drives inflammation, insulin resistance and small dense LDL. At SCVC, our GLP-1 programme targets VAT directly using personalised VAT scans and flexible dosing to improve long-term heart health.

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Hypothyroidism is a very common medical condition. Most patients symptoms improve with standard thyroxine treatment, however some do not. There are some genetic variations that leads to poor conversion of T4 to T3 (the active thyroid hormone).  It is not always possible to tell from TSH and T4 chemistry that this issue is present. This podcast covers a review article published in the Lancet in 2023. 

If you have an underactive thyroid and are taking thyroxine but have hypothyroid symptoms despite apparently 'normal' TSH and T4, especially if you struggle to lose weight and have raised blood cholesterol then it is possible that your T4 to T3 conversion is impaired and T3 supplements may make you feel a lot better. 

The relevance of T3 in the management of hypothyroidism

This podcast is a discussion around 
Guidance Document for GPs on Blood Pressure Management: Timeline of Events - where significant events and research in the evolution of blood pressure management guidelines, focusing particularly on heart failure. It aims to aid General Practitioners (GPs) in the UK in understanding the historical context and current standards for managing blood pressure across various patient demographics.