Eric Topol speaks with author Siddhartha Mukherjee about his latest book, The Laws of Medicine, and how uncertainty, imperfections, priors, outliers, and biases affect these laws.

Overall, PE is underdiagnosed, but Dr Goldhaber reviews a paper on overdiagnosis and provides suggestions on how to avoid it.

Dr Leana Wen, city health commissioner for Baltimore, speaks with Medscape Editor-in-Chief Dr Eric Topol about her work as an emergency medicine physician and public health advocate.

Patient deaths have been reported when healthcare providers confused tPA and TNK. Follow these suggestions to prevent any further mishaps.

Dr Goldhaber interviews Dr Pollack about the REVERSE-AD study evaluating a new dabigatran reversal agent and what the future holds for other NOAC reversal agents.

To avoid harmful medical interventions near the end of a patient's life, physicians need to follow ACP 'best practices' for talking to patients with serious illnesses about their care goals.

Eric Topol interviews Eric Schadt on how he turned math into medicine, and his need for speed both at and outside of work.

Eric Topol talks with New Yorker columnist and best-selling author Malcolm Gladwell on how best to tell the story of medicine.

Dr Jeffrey Berns reminds clinicians to be vigilant about the medications their patients take, both prescription and over-the-counter.

When the Antibiotic Resistance National Action Plan was announced, our readers had many concerns and questions. We asked CDC Director Tom Frieden for answers.