When the Antibiotic Resistance National Action Plan was announced, our readers had many concerns and questions. We asked CDC Director Tom Frieden for answers.

Occult magnesium deficiency may be responsible for innumerable ailments, but plasma and serum levels are unreliable measures. Dr Lundberg offers his advice for addressing this important problem.

A review of 30 RCTs reveals which nonpharmacologic interventions are and are not effective in reducing agitation.

The risk goes in both directions: Your patients traveling to or from the tropics could be at risk for -- or bringing back -- the chikungunya virus.

Evidence suggests that psychological treatments for depression in primary care can include less resource-intensive types of therapy.

Dr Silvio Inzucchi describes the ongoing quest to determine whether any diabetes medications might help lower cardiovascular risks.

A growing body of evidence shows that neuraminidase inhibitor antiviral drugs are effective against the flu, reducing complications and saving lives among hospitalized patients.

Dr Jo-Ann Manson describes the high-risk groups that should be screened for hypo- or hyperthyroidism.

Euan Ashley, self-described geek-turned-cardiologist, discusses how big data can help you practice smarter medicine.

Art Caplan and James Tallon discuss their view of changes in the past 5 to 6 years, the route we have to take going forward, and the role of physicians in achieving improvements.