Because the healthcare budget is not likely to get any bigger, Dr. John Marshall comments that we may need to 'clean the healthcare closet' to make room for new therapies. What can we do without?

Dr. Bruce Cheson comments on Walter Isaacson's biography Steve Jobs, finding a poignant lesson in the life and death of the entrepreneur whom the author calls a 'magician genius.'

Comments posted to a New York Times article about electronic medical records prompt Dr. Bruce Cheson to assess the pros and cons of EMRs.

Dr. Kathy Miller provides a short book review of Dr. Otis Brawley and Paul Goldberg's essential review of the US healthcare system.

Dr. Bruce Cheson and his fellows discuss The Emperor of All Maladies, Siddhartha Mukherjee’s book about the history of cancer, and pick the investigators whose contributions they find most compelling.

A Philadelphia doctor refused to recommend a kidney transplant for a mentally disabled 3-year-old girl. An ethicist talks about whether mentally challenged patients should receive organ transplants.

Dr. John Marshall says that his efficiency as a clinician is undermined as he spends more and more time entering data into the EMR with less and less administrative support. Is there a way out?

Henry R. Black, MD, and Roxana Mehran, MD, talked with Medscape after the 2012 State of the Union address about why healthcare was missing and what that portends.

Community health centers may already be ahead of the curve when it comes to care coordination, strengthening the healthcare workforce and the implementation of ACOs under the Affordable Care Act.

It has been 40 years since President Nixon signed the National Cancer Act. What have learned? What progress have we made? And what challenges lie ahead?