Meralgia Paresthetica Education and the PM&R Boards

This podcast episode from the NRAP Academy features Dr. David Rosenblum discussing Meralgia Paresthetica, a mononeuropathy affecting the lateral femoral cutaneous nerve. The condition involves entrapment or compression of this purely sensory nerve as it passes under the inguinal ligament near the anterior superior iliac spine, causing burning pain, tingling, and numbness in the anterior lateral thigh.

Key clinical points covered include the nerve's L2-3 origin from the lumbar plexus, common causes such as obesity, tight clothing, pregnancy, and diabetes, and the absence of motor weakness or reflex changes. Diagnosis is primarily clinical, though ultrasound can visualize nerve entrapment effectively.

Treatment approaches range from conservative management including weight loss, avoiding tight clothing, physical therapy, and neuropathic pain medications (gabapentinoids, duloxetine, tricyclics) to interventional procedures. Dr. Rosenblu strongly advocates for ultrasound-guided nerve blocks over fluoroscopic or blind approaches, citing better visualization and reduced risk of nerve trauma. Advanced treatments mentioned include peripheral neuromodulation and cryoablation for refractory cases.

The episode emphasizes that this condition is commonly tested on pain management board examinations (ABA, ABPM, FIPP, osteopathic boards) and can be significantly more painful and disabling than typically appreciated.

Upcoming Courses and Training Opportunities:

• Ultrasound training available at nrappain.org
• Regenerative medicine training courses
• Comprehensive PM&R Question Bank for Pain Management board preparation covering ABA, ABPM, FIPP, and osteopathic examinations
• CME credits available through the platform
• Clinical consultation services available at Dr. Rosenblum's Brooklyn office for patients seeking treatment

Meralgia Paresthetica Education and Clinical Guidance

• Overview:
• Focused on definition, anatomy, diagnosis, management, and board exam relevance for meralgia paresthetica.
• Anatomy and Pathophysiology:
• Nerve: lateral femoral cutaneous nerve (sensory only), typically arising from L2–L3.
• Course: traverses across the iliacus, passes under or through the inguinal ligament just medial to the ASIS, then enters the thigh.
• Sensory distribution: anterolateral thigh; anterior cutaneous division extends toward the knee.
• Etiology and Risk Factors:
• Common contributors: obesity, tight belts or clothing, pregnancy, prolonged sitting, diabetes, prior pelvic or hip surgery.
• Entrapment site: under the inguinal ligament near the ASIS (most frequent).
• Clinical Presentation:
• Symptoms: burning pain, tingling, numbness, dysesthesia localized to the anterolateral thigh.
• Provocation/relief: worse with standing or walking; relief with sitting or hip flexion.
• Neurologic exam: no motor weakness; no reflex changes.
• Diagnosis:
• Primarily clinical; Tinel's sign over the inguinal ligament may reproduce symptoms.
• EMG and nerve conduction studies are typically normal.
• Ultrasound: superficial nerve, generally easy to visualize, including in obese patients; can identify entrapment.
• Management Recommendations:
• First-line conservative care: weight loss; avoidance of tight belts/clothing; physical therapy; NSAIDs for inflammation.
• Pharmacologic options: gabapentin, pregabalin, duloxetine, tricyclic antidepressants; consider topical analgesic creams (e.g., lidocaine or anti-inflammatory combinations).
• Interventional approach:
• Ultrasound-guided nerve block is strongly recommended; the nerve lies lateral to the sartorius; real-time visualization enables precise, safe injection.
• Avoid fluoroscopic and blind approaches due to risk of further nerve trauma and post-procedure pain.
• Advanced interventions:
• Peripheral neuromodulation may provide benefit in select cases.
• Cryoablation has shown beneficial outcomes for the lateral femoral cutaneous nerve.
• Surgery is rarely required; options include neurolysis, decompression, or neurectomy as a last resort.
• Board Exam Preparation Emphasis:
• Key facts commonly tested:
• Involved nerve: lateral femoral cutaneous nerve.
• Nerve roots: L2–L3 (with population variants).
• Sensory-only nerve; absence of motor deficits.
• Compression site: under the inguinal ligament near the ASIS.
• First-line therapy: conservative measures; refractory cases: ultrasound-guided nerve block.
• Keywords to study: meralgia paresthetica; lateral femoral cutaneous nerve (also called lateral cutaneous nerve of the thigh).
• Practice Considerations:
• Severity: can be profoundly painful and disabling; often underappreciated.
• Referral: clinicians not trained in interventional techniques should refer patients to an interventionalist for diagnosis and treatment.

Decisions and Recommendations

• Ultrasound guidance is the preferred modality for lateral femoral cutaneous nerve interventions, superseding fluoroscopic or blind approaches.
• Rationale: superior visualization, real-time feedback, and reduced risk of nerve trauma and post-procedural pain.

Outreach and Resources

• NRAP Academy resources:
• Ultrasound training, regenerative medicine training, CME credits, and a comprehensive pain board question bank (ABA, ABPM, FIPP, osteopathic, and related exams).
• Clinical availability:
• Patient consultations for meralgia paresthetica offered in Brooklyn at www.AABPpain.com 718 436 7246 .