MGH Faculty Development Podcast

"Using Big Data and Causal Methods to Improve Clinical Practice"

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures offer the opportunity for women faculty from outside institutions that have hosted Anne Klibanski Scholars to present on their expertise, either alone or in tandem with an Anne Klibanski Scholar.

Presenter: Anthea Lindquist, MBBS, DPhil, Obstetrician/gynaecologist and perinatal epidemiologist, Mercy Hospital for Women, University of Melbourne, Australia

Learning Objectives: Upon completion of this activity, participants were able to:

• Gain an understanding of the potential role of causal inference methods in clinical decision-making.
• Gain an appreciation of how big data and causal methods can help answer difficult clinical questions in obstetric practice.
• Review the current gaps in pharmacoepidemiology in obstetrics and how these methods might be able to fill these gaps.

Click here to watch webinar.

"Insights into the pathophysiology and treatment of PCOS"

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures offer the opportunity for women faculty from outside institutions that have hosted Anne Klibanski Scholars to present on their expertise, either alone or in tandem with an Anne Klibanski Scholar.

Presenter: Chu-Chun Huang, MD, PhD, Assistant Professor, Department of Obstetrics and Gynecology, National Taiwan University Hospital

Learning Objectives: Upon completion of this activity, participants were able to:

• Briefly describe the diagnostic algorithm and assessment of polycystic ovarian syndrome (PCOS) based on the updated international evidence-based guideline in 2023.
• Illustrate the general concepts and some novel insights of the pathophysiology of PCOS based on our research works.
• Illustrate the most updated treatment for PCOS.

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“Neuroinflammation causes neuronal dysfunction by destabilizing excitatory synapses” and “Antigen-specific T cells in autoimmune inflammatory diseases of the central nervous system”

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures bring together faculty from institutions that have hosted Anne Klibanski Scholars with MGH scholars, on topics that overlap both research areas.

Dr. Gillani presented on “Neuroinflammation causes neuronal dysfunction by destabilizing excitatory synapses.”  Dr. Hastermann presented on “Antigen-specific T cells in autoimmune inflammatory diseases of the central nervous system.”

Presenters: Rebecca L. Gillani, MD, PhD, Instructor, Neurology, MGH/HMS Maria Hastermann, MD, PhD, Max Delbrück Center, Berlin

Learning Objectives for Dr. Gillani’s talk: Upon completion of this activity, participants were able to:

• Understand the contribution of neuronal dysfunction to neurologic disability in people living with multiple sclerosis.
• Recognize the scope of synaptic dysfunction in people living with multiple sclerosis.
• Identify potential mechanisms for neuronal dysfunction due to neuroinflammation.

Learning Objectives for Dr. Hastermann’ talk: Upon completion of this activity, participants were able to:

• Describe neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
• Recognize the role of T cells in central nervous system (CNS) inflammation.
• Review the longitudinal prospective registry study (example BERLimmun).

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“The future of vaginal microbiome interventions” and “Targeting the immune response at the cervicovaginal interface to prevent preterm birth”

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures bring together faculty from institutions that have hosted Anne Klibanski Scholars with MGH scholars, on topics that overlap both research areas.

Dr. Mitchell presented on “The future of vaginal microbiome interventions.”  Dr. Sykes presented on “Targeting the immune response at the cervicovaginal interface to prevent preterm birth.”

Presenters: Caroline M. Mitchell, MD, MPH, Associate Professor, Department of Obstetrics and Gynecology, MGH/HMS Lynne Sykes, PhD, Parasol Foundation Clinical Senior Lecturer in Obstetrics at Imperial College London

Learning Objectives for Dr. Mitchell’s talk: Upon completion of this activity, participants were able to:

• Participants will be able to identify gaps in the field of treatment for vaginitis.
• Participants will be able to describe novel treatments under development.
• Participants will be able to describe barriers to development of novel treatments.

Learning Objectives for Dr. Sykes’ talk: Upon completion of this activity, participants were able to:

• Appreciate the association between the vaginal microbiome and risk of premature birth.
• Be aware of the changes in the immune response at the cervicovaginal interface in women with an adverse vaginal microbiome and who deliver preterm.
• Acknowledge the potential new strategies for spontaneous preterm birth prediction and prevention.

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Faculty Transition Webinar Series Session 3 "Health of Your Wealth: Retiring against a backdrop of change"

The Faculty Transition Webinar Series sponsored by the Office for Senior Faculty Affairs addresses the many elements that come into play as faculty move toward retirement. This third session addressed the financial aspect of retirement. Learning Objectives: Upon completion of this activity, participants were able to:

• Provide a financial check-up for physicians in their 50’s and 60’s to help ensure they are on track for a successful retirement transition.
• Discuss advanced strategies to help maximize their future social security monthly benefit as well as key points about Medicare.
• Review recent changes in tax and estate law changes in MA.
• Share considerations when investing in the context of an election, war, deglobalization, and changing interest rates.

Presenter: Nora Yousif, CFP, CDFA, MBA, Financial Advisor and Senior Vice President of the Empower Wealth Group at RBC Wealth Management. Nora Yousif is a Financial Advisor and Senior Vice President of the Empower House Financial Group at RBC Wealth Management helping her clients make smarter decisions when it comes to their wealth planning and investments. She has presented on personal finance and investments for over 350 organizations including Mass General Brigham, Tufts Medical Center, Signature Healthcare, the IRS, MA Society of CPAs, and countless private medical practices. Nora frequently contributes to TV shows like Channel 5, CBS, NBC Boston, and Yahoo! Finance. Nora has been published in CNBC articles and MarketWatch. Nora was honored to be named a 2024 Best-in-State Top Women Wealth Advisor by Forbes*. Finally, she received her MBA from MIT Sloan, having been immersed with some of the brightest minds in the world of finance. Click here to watch webinar.

Click here for copy of her handout.

“Role of branched-chain amino acid catabolism in healthy and injured kidney“

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures offer the opportunity for women faculty from outside institutions that have hosted Anne Klibanski Scholars to present on their expertise, either alone or in tandem with an Anne Klibanski Scholar.

Presenter: Sian E. Piret, PhD, Assistant Professor, Division of Nephrology and Hypertension Renaissance School of Medicine, Stony Brook University

Learning Objectives: Upon completion of this activity, participants were able to:

• Understand the metabolic pathways used to generate ATP in healthy proximal tubule cells.
• Understand how these pathways change in the setting of AKI.
• Understand how the branched-chain amino acid (BCAA) catabolic pathway may be regulated.
• Understand the cellular and physiological consequences of altered BCAA catabolism.

Click here to watch webinar.

“Understanding the Natural History of Polycystic Ovary Syndrome: Insights from a Prospective Cohort, Project Viva”  “The genetics of type 2 diabetes in youth: Where we are and the road ahead”

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures bring together faculty from institutions that have hosted Anne Klibanski Scholars with MGH scholars, on topics that overlap both research areas.

Dr. Whooten presented on “Understanding the Natural History of Polycystic Ovary Syndrome: Insights from a Prospective Cohort, Project Viva.”  Dr. Srinivasan presented on “The genetics of type 2 diabetes in youth: Where we are and the road ahead.”

Presenters: Rachel C. Whooten, MD, Assistant Professor of Pediatrics, Division of Pediatric Endocrinology, Massachusetts General Hospital/Harvard Medical School Shylaja Srinivasan, MD, MAS, Assistant Professor of Pediatrics, Division of Pediatric Endocrinology, University of California, San Francisco

Learning Objectives for Dr. Whooten’s talk: Upon completion of this activity, participants were able to:

• To apply the Rotterdam Criteria to assess prevalence estimates of polycystic ovary syndrome among adolescent females within a longitudinal birth cohort, Project Viva.
• To characterize PCOS within this cohort.
• To understand the natural history of PCOS development among adolescent females in relation to adiposity and cardiometabolic biomarkers.

Learning Objectives for Dr. Srinivasan’s talk: Upon completion of this activity, participants were able to:

• Describe the epidemiology and pathophysiology of type 2 diabetes in youth.
• Evaluate the genetic architecture of type 2 diabetes in youth.
• Recognize key differences between type 2 diabetes in youth and adults.

Click here to watch webinar.

“Pediatric Heart Health: 4 High Impact Topics for General Pediatricians and Pediatric Cardiologists“

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures offer the opportunity for women faculty from outside institutions that have hosted Anne Klibanski Scholars to present on their expertise, either alone or in tandem with an Anne Klibanski Scholar.

Presenter: Hanano Watanabe, MD, MS, Assistant Professor and General Pediatric Cardiologist, Weill Cornell Medicine, New York

Learning Objectives: Upon completion of this activity, participants will be able to:

• Discuss the role of preventive cardiology in general and subspecialty pediatrics care.
• Discuss the role and impact of targeting modifiable childhood cardiovascular disease risk factors.
• Discuss recent advances in fetal cardiology.
• Discuss recent advances in pediatric cardiology.

Click here to watch webinar.

“Emerging Role of Contrast Enhanced Mammography”

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures offer the opportunity for women faculty from outside institutions that have hosted Anne Klibanski Scholars to present on their expertise, either alone or in tandem with an Anne Klibanski Scholar.

Presenter: Tali Amir, MD, Director, Breast Imaging Bergen, Memorial Sloan Kettering (MSK) Cancer Center. She is a board-certified diagnostic radiologist with specialized training in breast imaging. She practices at MSK Bergen in New Jersey, as well as at the Evelyn H. Lauder Breast Center in Manhattan

Learning Objectives: Upon completion of this activity, participants were able to:

• Describe the rationale and technique of Contrast Enhanced Mammography (CEM).
• Identify practical considerations and limitations of CEM.
• Understand the principles of CEM interpretation.

Click here to watch webinar.

“Enhancing the detection and treatment of anxiety disorders in autistic youth”“Assessment and Treatment of Anxiety in Williams Syndrome”

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures bring together faculty from institutions that have hosted Anne Klibanski Scholars with MGH scholars, on topics that overlap both research areas.

Dr. Kerns will present on “Enhancing the detection and treatment of anxiety disorders in autistic youth.”  Dr. Thom will present on “Assessment and Treatment of Anxiety in Williams Syndrome.” 

Presenters: Connor M. Kerns, PhD, Associate Professor, Department of Psychology, University of British Columbia, Vancouver, BC Robyn P. Thom, MD, Instructor, Department of Psychiatry, MGH/HMS

Learning Objectives for Dr. Kern’s talk: Upon completion of this activity, participants were able to:

• Describe similarities and differences in how anxiety disorders presented in autistic v. allistic (non-autistic) youth.
• Describe challenges to assessing anxiety disorders in autistic youth and the importance of autism-tailored anxiety measures.
• Describe the evidence base supporting adapted and traditional cognitive-behavioural therapy for anxiety in autistic children. 

Learning Objectives for Dr. Thom’s talk: Upon completion of this activity, participants were able to:

• To better understand the neurocognitive profile of individuals with Williams syndrome.
• Consider how cognitive behavioral therapy may be modified for individuals with Williams syndrome. 
• Discuss emerging psychopharmacologic treatments for anxiety in Williams syndrome.

Click here to watch webinar.