In Shakespeare's Romeo and Juliet, the nurse complains of a headache saying "Lord, how my head aches! what a head have I! It beats as it would fall in twenty pieces." In 1582, Bartholomew the Englishman's 13th century text was reprinted in London, describing a condition called "emigraina" that Bartholomew defined as "similar to hammers beating in the head." Whether it was called emigraina, head aches, or megrym, as some contemporary accounts have called it, it is plain that migraines were a common problem for Shakespeare's England, with proposed solutions ranging from mild tonics and elixirs, all the way to dangerous blood letting and even brain surgery. Here this week to help us understand the history of migraines, their diagnosis, and their treatment, for the 16-17th century is our guest and author of the chapter titled "History of migraine" in the Handbook of Clinical Neurology, Dr. Peter Koehler.

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