Eight healthy babies have been born in the UK thanks to an IVF treatment that Professor Doug Turnbull and others pioneered over many years.

What inspired Doug’s impactful career? The patients he saw along the way.

Following the recent headline news of his work, he shares what the results mean to him.

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The Centres for Antimicrobial Optimisation Network is a research collaboration involving institutions around the world. They aim to tackle antimicrobial resistance through interventions and practices that matter to communities most affected by it. Alison Holmes, the network’s lead, shares how they make the collaboration work across different countries.

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Tackling global health challenges like antimicrobial resistance (AMR) requires interventions and practices that matter to the communities affected.

CAMO-Net (Centres for Antimicrobial Optimisation Network) is a Wellcome-funded research collaboration between several institutions around the world that’s putting communities at the heart of their work.

In this Wellcome Guest Lecture, researchers Alison Holmes, Senjuti Saha and Andrew Kambugu discuss the network’s mission, the work they’re doing in Uganda and Bangladesh and how data will enable policy changes.

Chapter titles:

00:00 Intro

00:34 The problem of AMR

02:39 Creating a global research network

04:11 Representing global locations

05:26 Knowledge to influence policy

06:14 The network's priorities

07:48 Creating equitable partnerships

09:09 The work in action

10:00 The network's learnings so far

11:40 Work in Uganda and South Africa

12:07 Impact on policy

12:57 What's next for the network?

14:24 Q&A: The network's impact in Bangladesh

18:52 Q&A: The network's work in Uganda

22:22 Q&A: Co-creating a programme with communities

27:31 Q&A: Challenges of a global network

29:58 Q&A: Data for policy-level changes

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🔗 MORE FROM WELLCOME:

Wellcome is a global charitable foundation. We want everyone to benefit from science’s potential to improve health and save lives.

Read our latest stories, opinions and reports: https://wellcome.org/news-and-reports

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Wellcome’s Modi Mwatsama says there’s not enough research on interventions to address the health impacts of climate change.

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Would you use an AI therapist?

Chatbots have been advancing for decades. They could completely transform access to mental health care. But we should approach it with caution to make sure its potential is realised in the right way.

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An inspiring discovery is challenging conventional thinking. Find out more in our podcast: When Science Finds a Way #SciencePodcast #Podcast #Dengue

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Ben Bleasdale and Sophie Gilbert share some of the wisdom they’ve used when changing careers from researcher to policy.

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And is it really humans versus AI? 

In our newest explainer video, we dive deep into the conversation around AI therapy – joined by Professor Miranda Wolpert, Dr Joyce Nakatumba-Nabende and Shuranjeet Singh.

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And is it really humans versus AI?

Chatbots have been advancing for decades, ready to talk whenever we need them. With most mental health therapy built on conversation, it’s not surprising that more of us are turning to these bots for support.

However, not everyone’s convinced.

With the right approach, chatbots could completely transform access to mental health care.

But many people are more cautious, concerned about unhelpful or harmful interactions, inappropriate regulation and widening health inequalities. So where do we go from here?

In our newest explainer video, we dive deep into the conversation around AI therapy – joined by Professor Miranda Wolpert, Dr Joyce Nakatumba-Nabende and Shuranjeet Singh.

📚 SOURCES AND READING:

Read Professor Miranda Wolpert’s latest article on AI and mental health treatment: https://wellcome.org/news/ai-and-mental-health-help-revolutionise-treatments

In the introduction, we referenced some digital interventions for psychosis and PTSD:

https://wellcome.org/news-and-reports/podcast/episode-5 https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03569-8

We shared details of AVATAR therapy, which helps patients with psychosis find new ways of relating to the voices they hear. You can find more information about it here: https://www.kcl.ac.uk/news/spotlight/the-power-of-digital-avatars-in-psychosis-therapy

To read more on different user experiences with mental health chatbots: https://www.nature.com/articles/s44184-024-00097-4 https://humanfactors.jmir.org/2022/2/e35668

For the study that concluded medically-trained chatbots could help people reframe negative thoughts: https://arxiv.org/abs/2305.02466

Or the study that found chatbots might be just as effective as human therapists for those with depression, anxiety or eating disorders: https://www.technologyreview.com/2025/03/28/1114001/the-first-trial-of-generative-ai-therapy-shows-it-might-help-with-depression/

The Guardian provide a useful summary of the study by OpenAI and MIT, talking about loneliness and isolation in chatbot users: https://www.theguardian.com/technology/2025/mar/25/heavy-chatgpt-users-tend-to-be-more-lonely-suggests-research

For more information and statistics about the NHS chatbot: https://transform.england.nhs.uk/key-tools-and-info/digital-playbooks/workforce-digital-playbook/using-an-ai-chatbot-to-streamline-mental-health-referrals/

We referenced an article about a chatbot for people with eating disorders: https://www.nytimes.com/2023/06/08/us/ai-chatbot-tessa-eating-disorders-association.html

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Researchers share their advice for anyone considering a career researching climate and health.

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