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In our previous episode, we spoke with Dr. Sarah Das, a Scientist Emeritus at Woods Hole Oceanographic Institution, about how climate change is affecting the big polar ice sheets of Antarctica and Greenland. She’s been traveling to the poles for her research since the nineties, and this week, she’s taking us behind the scenes: into the world of glacier science, “boomerang flights,” and ice as far as the eye can see.
A video version of this episode is available on our YouTube channel. For a deeper dive and additional resources, visit: https://climate.mit.edu/podcasts/bonus-ice-sheets-polar-scientist.
For more episodes of Ask MIT Climate, check out askmitclimate.org. Plus, find us on Instagram, TikTok, and YouTube for outtakes, bonus content, and more climate knowledge from MIT. As always, we love hearing from our listeners; email us at [email protected].
Dr. Daniel Braconnier discusses with Dr. David Hsu about the importance of understanding the electrical grid and its role in the future of energy systems. It explores the complexity of the grid, its historical development, and the challenges and opportunities it presents. This Why THIS Matters episode highlights the inter-dependencies between different energy sources and the need for a coordinated approach to managing the grid. It also addresses common misconceptions about the grid, such as thinking it is a unitary object or separate from other systems. The episode concludes by emphasizing the significance of the grid in the context of climate change and the need for a comprehensive understanding of how the grid is built and how it can be changed to achieve future goals. Why THIS Matters is an MIT Learn Podcast, continue to learn more at: https://learn.mit.edu/
We’ve all been there. You’re having an adult beverage, and suddenly, you feel the urge to “go”... and after you go once, you're making repeated trips to the bathroom all night. This is the legendary concept of “Breaking the Seal.” But is it actually real? Is there a physical barrier inside us that, once broken, opens the floodgates? If not, what's actually happening behind the scenes? Dr. Jeffrey Held joins the pod to help us unravel the mysteries of our own plumbing.
Learn more about Jeffrey Held, MD
Understanding how bacteria evade our immune systems and cause disease is vital for developing better treatments and diagnostics. In this MIT Learn Beyond Biology episode, MIT professor Becky Lamason shares her insights on bacterial pathogens, their interaction with human cells, and the future of infectious disease research. This discussion reveals not only the complexity of microbes but also how innovative science can uncover new paradigms in host-pathogen interactions. Stay to the end to learn more about Becky’s personal path to the lab.
Resources:00:00 - The unpredictability of pathogens and their survival strategies
00:24 - Introduction to Becky Lamason and the importance of bacterial pathogens
01:08 - Common bacterial pathogens and infections in daily life
01:33 - Food recalls and bacterial contamination in the environment
02:13 - Focus on Listeria monocytogenes and clinical implications
02:41 - Other bacteria like Rickettsia and their deadly potential
03:15 - Symptoms of spotted fevers caused by Rickettsia
03:20 - The range of bacterial disease symptoms and severity
04:01 - Categorizing pathogens: bacteria, viruses, fungi, and parasites
04:28 - Bacteria’s size relative to other microbes and complexity
05:04 - The diversity within bacterial pathogens and their unique features
05:20 - Treatment options for bacterial infections and antibiotic sensitivity
05:48 - Antibiotic resistance: evolution, biology, and clinical impact
06:26 - Practical advice: importance of completing antibiotic courses
08:02 - The analogy of pathogens as cell biologists and their survival tactics
08:41 - Bacteria’s ability to break rules of host cell biology
11:25 - Comparing bacterial size to human cells; visualization of scale
12:19 - How bacteria enter human cells through force or mimicry
12:33 - The dependency of certain bacteria on living inside host cells
15:28 - Transmission cycles involving ticks and environmental reservoirs
17:28 - Mechanisms of bacterial cell spreading and invasion strategies
19:00 - The concept of acute infection phases and bacterial proliferation
20:14 - The ultimate goal of bacteria: replication and dissemination
21:28 - Safety measures in the lab working with pathogenic bacteria
23:33 - Connecting basic research to clinical applications and diagnostics
25:09 - The power of microscopy and visual data in understanding infection
27:38 - Memorable discoveries and unexpected breakthroughs in the lab
29:28 - Future tech: genome editing, large-scale genetic analysis, and new directions
31:33 - The significance of bacteria targeting host cell organelles like ER and nuclei
33:01 - Becky’s journey, switching questions and embracing multidisciplinary work
35:41 - Building community and embracing the unknown in scientific research
37:25 - From high school curiosity to MIT professor: Becky’s personal story
39:56 - Balancing real-world jobs and academic pursuits
42:12 - The future of bacterial research: new tools and broader applications
44:02 - Final thoughts and encouragement to explore and collaborate
The frozen parts of our planet—from sprawling polar ice sheets and floating sea ice to mountain glaciers and frigid soils—face profound risks from climate change. Already, a warmer world has transformed these landscapes, with consequences that span the globe. Dr. Sarah Das, a Scientist Emeritus at Woods Hole Oceanographic Institution, joins to discuss her decades-long career studying the Antarctic and Greenland ice sheets and help us understand how changes to the polar regions affect people now and in the future.
We thank WHOI for providing audio recorded during supraglacial lake research in Greenland. (Credit: Chris Linder, ©Woods Hole Oceanographic Institution).
For a deeper dive and additional resources related to this episode, visit: https://climate.mit.edu/podcasts/e8-polar-ice-warming-world.
For more episodes of Ask MIT Climate, check out askmitclimate.org. Plus, find us on Instagram, TikTok, and YouTube for outtakes, bonus content, and more climate knowledge from MIT. As always, we love hearing from our listeners; email us at [email protected].
On today's episode, we're joined by Dr. Bruce Cameron. He's the director of the system architecture group, a senior lecturer, and the faculty director for MIT's Architecture and System Engineering Online Certificate Program.
In this episode, we'll explore the world of systems thinking, what it really means to see the connections between events, why the decisions you make early in any complex system can determine everything that follows, and how organizations consistently undermine themselves by optimizing the wrong things. From NASA to Amazon to Meta, Bruce has seen systems succeed and fail at the highest levels, and he's here to share what he's learned, including some surprises along the way.
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