MIT OpenCourseWare: Free Courses from the institute

MIT OpenCourseWare: Free Courses from the institute

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MIT OpenCourseWare: Free Courses from the institute episodes

  • 7B. Protein 1: 3D Structural Genomics, Homology, Catalytic and Regulatory Dynamics, Fun...

    MIT HST.508 Genomics and Computational Biology, Fall 2002
    Instructor: George Church
    View the complete course: https://ocw.mit.edu/courses/hst-508-genomics-and-computational-biology-fall-2002/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61gaHWysmlYNeGsuUI8y5GV

    Uploaded 22-08-22

    We'll go from a very accurate sequence to a probably less than accurate speculative league and specificity, to actually how we actually do get a 3D structure league and specificity, and some of the methods that are shared by the computational tools.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW‚ YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.



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    49 min
  • Lecture 6: Fiat-Shamir Paradigm and Zero-Knowledge Proofs, Part 2

    MIT 6.5630 Advanced Topics in Cryptography, Fall 2023
    Instructor: Yael T. Kalai

    Uploaded 29-01-25

    View the complete course: https://ocw.mit.edu/courses/6-5630-advanced-topics-in-cryptography-fall-2023/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61EZllk7zwgvPbI4kbnKhWz

    This lecture continues the topics of proving the Merkel has is collision resistant, eliminating interaction via the fiat-Shamir paradigm, and proving the soundness of the Kilian-Micali protocol in ROM.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.

    Speakers: Yael T. Kalai



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    1 hr 16 min
  • 3A. DNA 1: Genome Sequencing, Polymorphisms, Populations, Statistics, Pharmacogenomics...

    MIT HST.508 Genomics and Computational Biology, Fall 2002
    Instructor: George Church
    View the complete course: https://ocw.mit.edu/courses/hst-508-genomics-and-computational-biology-fall-2002/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61gaHWysmlYNeGsuUI8y5GV

    Uploaded 22-08-22

    We'll start with types of mutants and how they're represented for bioinformatic purposes. We'll talk about the three main methods by which mutations occur, drift, and select.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW‚ YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.



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    1 hr 7 min
  • Lecture 9: BARGs Implies SNARGs and Connection to Non-Signaling PCPs, Part 2

    MIT 6.5630 Advanced Topics in Cryptography, Fall 2023
    Instructor: Yael T. Kalai

    Uploaded 29-01-25

    View the complete course: https://ocw.mit.edu/courses/6-5630-advanced-topics-in-cryptography-fall-2023/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61EZllk7zwgvPbI4kbnKhWz

    This lecture continues the topics, including BARGs implies SNARGs and connection to non-signaling PCPs.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.

    Speakers: Yael T. Kalai



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    1 hr 21 min
  • 3B. DNA 1 : Genome Sequencing, Polymorphisms, Populations, Statistics, Pharmacogenomics...

    MIT HST.508 Genomics and Computational Biology, Fall 2002
    Instructor: George Church
    View the complete course: https://ocw.mit.edu/courses/hst-508-genomics-and-computational-biology-fall-2002/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61gaHWysmlYNeGsuUI8y5GV

    Uploaded 22-08-22

    We're going to go through an example of association studying, the chi-square statistic in the simplest case. That simple case will be a single allele combination, two alleles and two possible phenotypic outcomes, HIV resistance and HIV non-resistance.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW‚ YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.



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    54 min
  • Lecture 6: Fiat-Shamir Paradigm and Zero-Knowledge Proofs, Part 1

    MIT 6.5630 Advanced Topics in Cryptography, Fall 2023
    Instructor: Yael T. Kalai

    Uploaded 29-01-25

    View the complete course: https://ocw.mit.edu/courses/6-5630-advanced-topics-in-cryptography-fall-2023/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61EZllk7zwgvPbI4kbnKhWz

    This lecture covers the topics of proving the Merkel has is collision resistant, eliminating interaction via the fiat-Shamir paradigm, and proving the soundness of the Kilian-Micali protocol in ROM.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.

    Speakers: Yael T. Kalai



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    1 hr 40 min
  • 8B. Protein 2: Mass Spectrometry, Post-synthetic Modifications, Quantitation of Protein...

    MIT HST.508 Genomics and Computational Biology, Fall 2002
    Instructor: George Church
    View the complete course: https://ocw.mit.edu/courses/hst-508-genomics-and-computational-biology-fall-2002/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61gaHWysmlYNeGsuUI8y5GV

    Uploaded 22-08-22

    For today, we've basically tried to integrate the protein, either absolute or ratios, with RNA measurements and with metabolite interactions, proteins post-synthetic modifications.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW‚ YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.



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    59 min
  • Lecture 4: PCP via GKR and Interactive Arguments, Part 2

    MIT 6.5630 Advanced Topics in Cryptography, Fall 2023
    Instructor: Yael T. Kalai

    Uploaded 29-01-25

    View the complete course: https://ocw.mit.edu/courses/6-5630-advanced-topics-in-cryptography-fall-2023/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61EZllk7zwgvPbI4kbnKhWz

    This lecture continues the topics, including the probabilistically checkable proofs (PCP), definition and construction from GKR and the interactive succinct argument for NP.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.

    Speakers: Yael T. Kalai



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    1 hr 18 min
  • 5C. RNA 1: Microarrays, Library Sequencing and Quantitation Concepts

    MIT HST.508 Genomics and Computational Biology, Fall 2002
    Instructor: George Church
    View the complete course: https://ocw.mit.edu/courses/hst-508-genomics-and-computational-biology-fall-2002/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61gaHWysmlYNeGsuUI8y5GV

    Uploaded 22-08-22

    We will review how far the in-situ might go, and what its current limitations might be. And then we'll move on to arrays. One potential advantage to in-situ analyses is that you actually monitor them real time.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW‚ YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.



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    59 min
  • Lecture 7: Soundness of the Fiat-Shamir Paradigm in the Standard Model, Part 2

    MIT 6.5630 Advanced Topics in Cryptography, Fall 2023
    Instructor: Yael T. Kalai

    Uploaded 29-01-25

    View the complete course: https://ocw.mit.edu/courses/6-5630-advanced-topics-in-cryptography-fall-2023/
    YouTube Playlist: https://www.youtube.com/playlist?list=PLUl4u3cNGP61EZllk7zwgvPbI4kbnKhWz

    This lecture continues the topics, including the definition of CI hash functions, existence in the ROM and simple counter example in the plain model.

    License: Creative Commons BY-NC-SA
    More information at https://ocw.mit.edu/terms
    More courses at https://ocw.mit.edu
    Support OCW at http://ow.ly/a1If50zVRlQ

    We encourage constructive comments and discussion on OCW’s YouTube and other social media channels. Personal attacks, hate speech, trolling, and inappropriate comments are not allowed and may be removed. More details at https://ocw.mit.edu/comments.

    Speakers: Yael T. Kalai



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    1 hr 12 min

About MIT OpenCourseWare: Free Courses from the institute

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A free and open online publication of educational material from thousands of MIT courses, covering the entire MIT curriculum, ranging from introductory to the most advanced graduate courses. On the…