Models & Agents
Claude designed novel protein binders from scratch for 14 of 15 targets, with 22-35% success rates that beat the field's typical 10-15%.
What You Need to Know: Anthropic demonstrated Claude autonomously creating functional protein binders that were then built and validated by Adaptyv Bio and Twist Bioscience. Open-weight releases from Ornith and inclusionAI add new dense and MoE options for local use. ...
Chapters:
0:00 Intro
0:15 Introduction
1:38 Ornith-1.5 family (9B dense, 35B MoE, 397B MoE)
2:20 Ling-3.0-tiny-base and Ling-3.0-flash-base checkpoints
3:16 Kimi K3 1M-token context window evaluation
3:54 Qwen3.8-27B Dynamic v3 Unsloth GGUFs
4:24 Droidrun Android automation
5:10 ForwardLane agentic AI scaling program
6:04 Beijing AI bar DeepSeek experiment
6:34 llama.cpp --n-cpu-ffn option PR
7:35 Under the Hood
10:31 Tomorrow Teaser
10:42 Closing
AI Disclosure: This podcast is curated by Patrick but uses AI-generated voice synthesis for audio production.
🎬 Watch on YouTube: https://www.youtube.com/watch?v=FQQd1T5Wgm8
📝 Full show notes, transcript & sources: read the episode page
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