Mike Lynch and colleagues published a paper that is devastating to thousands of past studies on natural selection. By sequencing DNA from multiple natural populations over several years, they showed that the net effect of natural selection is “zero” for most genetic variants. They caution that selection pressures in the natural world fluctuate. This cause the chromosomal targets of selection to shift over time, etc., meaning that many thousands of scientific studies that found evidence for natural selection are probably wrong. This paper is a gold mine of quotes, so Dr Rob quotes it extensively.

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