Biblical Genetics

Natural selection comes in two forms, positive and negative. Positive selection is supposed to improve species, but Dr Rob gives a clear example where bad mutations are amplified. Negative selection is supposed to keep species from degrading, but Dr Rob uses the same example to show how it occurs too late. Based on an article from Creation.com.

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Scientist throw around words and phrases that are sometimes hard to understand. This is not one of them. Genetic drift is an easy concept. Dr Rob brings up the example drift among of human mitochondria, perhaps the most extreme form anyone has ever seen. And, since natural selection is generally weak, genetic drift overwhelms selection at critical junctures during development. This has profound implications for the creation-evolution debate, but first, the explanation…

Source paper under discussion: Árnadóttir et al. 2024, The rate and nature of mitochondrial DNA mutations in human pedigrees, Cell 187(15):3904-3910.

Fig 1: Mutant mitochondrial frequencies in child (y) vs mother (x), from the supporting data of the paper above.

Fig 2: Histogram of frequency changes from mother to child, same source as above.

Fig 3: Histogram data for each frequency bin in the mother (legend) vs child (x). Same source as above.

One woman is the ancestress of all living people. They call her Eve. Is she the Eve of the Bible? How long ago did she live? Join Dr Carter as he explains how scientists struggle to assign a date to Eve. It may come as a surprise, but the ‘date’ is based on questionable assumptions and debatable philosophy. All we can know is that the mutation rate is quite high and the mutation removal rate is quite low. Thus, science tells us that Eve lived not many thousands of years ago.

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Even though it was completed a quarter century ago, geneticists still struggle to estimate the number of genes in the human genome. They went from ‘hundreds of thousands’ to “22 thousand”, then more recently to “about 19,500”. The number, however, has just exploded. Tens of thousands of new genes with important functions were discovered hiding in the ‘junk DNA’. Dr Rob explains what these new findings mean to the creation-evolution debate.

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In a recent presentation on human-chimp similarities to LOGOS Research Associates, I made the (correct) claim that most new mutations are lost. An opponent attempted to make hay of this, claiming it disproves the ‘creationist’ calculations of the time to Y Chromosome Adam and Mitochondrial Eve. What he failed to understand, however, is that the Y and mt chromosomes are haploid and behave very differently to the rest of the genome. In fact, mutations occur in them in a ratchet-like manner and no degree of natural selection can change that. Do you want a lesson in population genetics? Tune in!

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In a recent Creation magazine article, I talked about an interesting new case study done on one of the world’s most favorite cheeses, Brie, and its relatives Camembert and Roquefort. A long time ago, cheesemakers unknowingly selected non-sexually reproducing fungal lines for these cheeses. Now, many decades later, mutations have built up in this lines to the point where they are starting to have trouble reproducing. Rescue efforts are underway, but in the meantime this gives us an object lesson about the impossibility of evolution, specifically the survival of the first organisms, which would not have been able to go through sexual recombination.

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Gregor Mendel was the father of modern genetics. He wrote his most important papers on the topic just a few years after Darwin published the Origin of Species. What people don’t realize is that Mendel’s papers did not only describe how traits are passed down. He also explained how his ideas of genetics lead directly to an explanation of the origin of species. Was Mendel directly and purposefully contradicting Darwin?

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Dr Carter spent some time recently in New Zealand. While there, he stopped by a giant colony of gannets. These sea birds number in the millions but they create a bit of a taxonomic mystery. Are three living species of gannets and the eight living species of booby one ‘created kind’? What about the cormorants? Should they also be included? Baraminology has not revealed the limits of the created kinds, so we have much work still to do.

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It is only natural for people to want to compare the Table of Nations (Genesis 10) to geography, linguistics, ancient history, and/or patterns in human DNA. The solution, however, is harder than most people think. Here, I list multiple reasons why it might actually be impossible to know where Shem, Ham, and Japheth belong even though Genesis is true.

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Additional references can be found in the main article.

The woolly mammoth is strongly associated with the Ice Age, but they survived until surprisingly recent times in the far north. Recently, the genomes of multiple mammoths from the last surviving population on Wrangel Island were sequenced. The scientists concluded the population was founded by 8 or fewer individuals and only 1 mitochondrial lineage was among them. They also estimated that the population grew to a few hundred before finally going extinct. This, it turns out, is a wonderful natural laboratory for biblical events. Consider that there were only 8 people on the Ark. How much genetic diversity would we expect to lose? Is that population too small to prevent so much inbreeding that humans would have gone into mutational meltdown? Etc. Etc.