Nerra Voices

Nerra Voices

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Nerra Voices episodes

  • Ep4: Stuart Berkowitz — Translating scattered trial data into a public Bayesian atlas that models…
    Stuart Berkowitz says his public Bayesian models deliver an extra life year for 3.5 cents—far below any charity he has examined—by combining scattered trial data into joint probabilities that remove overlapping effects across interventions. He built 93 separate causal oracles that treat aging itself as a disease state and project optimized personal protocols reaching 111–135 years. The entire atlas is published so every assumption, extrapolation, and cross-correlation adjustment remains open to inspection.
    • He started with VO2-max data from 122,000 Cleveland Clinic patients showing a 92 % all-cause mortality reduction at six standard deviations above the mean, then layered additional factors while subtracting cross-correlations.
    • From 25 interventions the combinatorial space reaches 32 million possible bundles; front-door, back-door, and eigenvalue analyses on mechanism-of-action graphs are used to avoid double-counting benefits.
    • Eigenvalue analysis removes most confounding, after which a measured 30–70 % residual correlation cut is applied and published inside each oracle.
    • The site grew 51 % month-over-month with under $500 spent and no marketing, driven by visitors proxy-entering data for chronically ill friends or relatives.
    • NHANES records are run through the oracles to quantify the gap between actual and optimal care; that gap is converted to life years via Social Security mortality tables and discounted by observed 50 % prescription adherence.
    • Supplements show almost no role in disease-progression reduction for most conditions, though osteoarthritis, BPH, and preeclampsia register small measurable effects.
    • A typical GP’s 300 chronic patients give doctors roughly 300-fold leverage over individual visitors when they adopt the Pareto-optimal lists.
    Stuart Berkowitz builds and maintains the public Bayesian oracles at longevityresearch.ca that model maximal life-year gains across 93 diseases.
    32 min
  • Ep3: Scott Pulcini — A scalper who once handled a tenth of E-mini volume rebuilt a durable edge by…
    Scott Pulcini once lost $800,000 in minutes on two separate days after breaching his own $100,000 daily loss limit instead of stopping. He rebuilt a durable edge after algorithms erased his original speed advantage by shifting from visible counterparties to reading stop runs and iceberg orders through CME MBO data on Bookmap, then codified the resulting rules into courses for retail traders.
    • Scott once averaged 50,000 contracts a day—roughly 10 percent of E-mini S&P volume—by placing orders throughout the book and scalping around them while seeing every counterparty.
    • After house numbers vanished, he adopted 2016 CME MBO data that reveals iceberg orders with certainty and treats them as the next-best proxy for where large entities are accumulating.
    • He only acts on a stop or iceberg event inside zones that meet market-specific volume thresholds (700 contracts for S&P icebergs, 150 for crude or gold) drawn from nine years of observation.
    • Entry waits for price to clear 115 percent of the five-minute ATR outside the zone; the stop sits on the far side so any breach must first clear trapped traders and the full volume event.
    • The “dumb and dumber” setup flags retail stop runs that appear as strong initiative buying on candles but are usually liquidation that reverses once the ATR filter fails to confirm follow-through.
    • A “sexy GEXie” adds conviction when a stop run lands at a heavy gamma level where options dealers must hedge, while reversion trades scalp back to the same volume event.
    • Scott’s grandfather’s line “lose your head, lose your ass” became literal when two rule breaches cost him $800,000 apiece instead of the planned $100,000 daily stop.
    Scott Pulcini is a former high-volume futures scalper who now teaches retail traders his stop-iceberg methodology and related strategies.
    45 min
  • Ep2: Dr. Michael Brandt — Inside a dual-certified facial plastic surgeon's practice where skin-cancer reconstruction and elective facelifts share the same anatomy and demand identical standards for natural function.
    In his Nerra Voices interview, Dr. Michael Brandt states that skin-cancer reconstruction and elective facelifts demand identical precision in tissue handling, planning, and scar camouflage because both must meet the same functional and aesthetic standard. He describes this shared requirement through the “supermarket test,” where a successful result lets the patient pass unnoticed so that others see the person rather than the work. The discussion also covers how his MSc research on scars changed his daily evaluation of outcomes and why he treats fillers and surgery as distinct tools rather than substitutes.
    • Dr. Brandt notes that reconstruction after cancer removal often requires creative tissue movement to preserve surrounding structures, while aesthetic cases allow more control over incision placement, yet both receive the same attention to detail.
    • His MSc work on scar assessment showed that the overall gestalt—how a scar sits relative to facial contours and affects expression—drives patient perception more than isolated factors such as color or texture.
    • He applies the supermarket test to decide when a repair has failed: any distortion of eyelid position or unnatural tension means the result draws attention instead of blending in.
    • Fillers can camouflage a nasal bump or restore volume but cannot reposition descended tissues or remove excess skin, so he does not use repeated injections as a bridge when structural correction is needed.
    • Training and dual certification required years of delayed personal time; he now prioritizes evenings and family activities after health issues reminded him where his primary responsibility lies.
    • Every case, whether reconstructive or cosmetic, creates an ongoing relationship because the surgeon continues to worry about long-term results rather than completing a one-time intervention.
    Dr. Michael Brandt is a dual-certified facial plastic and reconstructive surgeon at FORM Face + Body in Toronto.
    25 min
  • Ep1: Viktor Popovic — An immigrant founder who rebuilt after losing Google traffic overnight now routes merchant payments in real time to expose the hidden fees his first company’s margins never revealed.
    Viktor Popovic rebuilt after 21 years running Ultimate Washer by creating Avendo, a platform that routes each merchant transaction in real time across multiple processors so the lowest price wins without any lock-in. The most striking detail is that he now charges processors only ten cents per successful transaction and nothing to merchants, a direct response to the opaque statements and stagnant rates he accepted for over a decade.
    • After 14 years with one processor, Viktor saw volume grow while rates stayed fixed because statements were four to ten pages of line items that owners handed to accountants rather than challenge.
    • Avendo collects one application and set of documents, then forwards them to multiple processors; once several underwrite the merchant, the system lets those processors bid live on every card transaction.
    • The merchant dashboard shows only the final approved amount, statement, and chargeback tools; all routing logic, fallback decisions, and price responses stay hidden in the backend and complete in milliseconds.
    • A queue was added after live testing showed that transaction logging, not authorization, created stalls; the two backend teams met, mapped the bottleneck, and inserted the queue so results could be written without blocking the flow.
    • Weekly rotating tests now run across system segments to catch similar issues before they scale, because the architecture must duplicate cleanly for future markets such as Canada.
    • Viktor’s prior experience with seven separate product databases taught him that disconnected tools force constant manual updates; Avendo’s teams therefore meet at least weekly to keep every new component on a single source of truth.
    Viktor Popovic is Founder and President of Avendo.
    Find Viktor Popovic:
    LinkedIn: https://www.linkedin.com/in/viktor-popovic-b8a6b416
    33 min

About Nerra Voices

From the publisher's feed

Real people on the work they've chosen, interviewed live by Mira, the Nerra Network's AI host. Founders, clinicians, tradespeople, teachers, artists and organizers on what they do and what they've…