Dr. Nathan Dalton interviews Dr. Joseph Sia on the topic of radiation hypofractionation – its history, current clinical landscape, and potential future developments for patients with gliomas.

Shahad Abdulsahib discusses the findings of a recent paper, entitled "Transcriptional regulation of protein synthesis by mediator kinase represents a therapeutic vulnerability in MYC-driven medulloblastoma", which was published in Nature Communications in December 2025.

Dr. Rachna Malani interviews Mindy Freund about her work at the American Brain Tumor Association

Dr. Jasmin Jo interviews Dr. Amy Smith and Dr. David Ellison on their manuscript, entitled "Phase 3 randomized trial of post-irradiation chemotherapy in patients with newly diagnosed ependymoma, a report from the Children's Oncology Group" published in Neuro-Oncology in December 2025.

Dr. Dave Rogawski interviews Dr. David Solomon on his research that sheds light on how key genomic alterations in high-grade glioma evolve over time and how these insights might inform therapeutic development.

Dr. Haseeb Mehmood discusses the use of microbubble-enhanced transcranial focused ultrasound combined with standard temozolomide in high-grade glioma.

Dr. Evan Noch interviews Dr. Lisa DeAngelis about her career in neuro-oncology, role as Chair of Neurology and Physician-in-Chief at Memorial Sloan Kettering Cancer Center, and advice for trainees entering the field.

Dr. Iyad Alnahhas interviews Drs. David Schiff and Ranjit Bindra about their recent manuscript entitled "Phase I/II and Window-of-Opportunity Study of Pamiparib and Metronomic Temozolomide for Recurrent IDH Mutant Gliomas", published online in Neuro-Oncology in October 2025.

In this episode, Dr. Evan Noch and Dr. Maya Graham discuss the exciting new podcast subtypes and the episodes to come.

Description: Dr. Iyad Alnahhas interviews Dr. Charlotte Sleurs about her and her team's recent manuscript entitled: "Radiotherapy-induced neurocognitive decline among adult intracranial tumor patients: A voxel-based approach", published online in Neuro-Oncology in May 2025.