Wired to be Weird

NeuroByte - Neurons talking like viruses, & is your mind's eye blind?


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Electron microscope images of the neuronal protein, Arc, forming structures that resemble those typically associated with viral capsids. From: The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. Pastuzyn, Elissa D. et al. Cell , Volume 172 , Issue 1 , 275 - 288.e18

If I ask you to visualize a butterfly, what kind of an experience do you have? How clearly do you see it, if you see it at all?

NeuroBytes - Neurons talking like viruses & is your mind's eye blind?
Ian McLaughlin & Bo Allen

This is the first "NeuroByte" episode, where Bo and Ian discuss multiple topics without diving quite as deeply into the details. This week, we discuss a recent discovery that neurons appear to be capable of trading genetic material to one another, representing a novel mechanism by which neurons can communicate information to one another. Next, we discuss a poorly understood possible condition termed "aphantasia", a condition characterizing individuals who are entirely incapable of visualizing an imagined image - a population of people among whom Ian may well be counted.

 

Primary reading:

  1. Pastuzyn ED, Day CE, Kearns RB, Kyrke-Smith M, Taibi AV, McCormick J, Yoder N, Belnap DM, Erlendsson S, Morado DR, Briggs JAG, Feschotte C, Shepherd JD. The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. Cell. 2018 Jan 11;172(1-2):275-288.e18. doi: 10.1016/j.cell.2017.12.024. PubMed PMID: 29328916.
  2. Zeman A, Dewar M, Della Sala S. Lives without imagery - Congenital aphantasia. Cortex. 2015 Dec;73:378-80. doi: 10.1016/j.cortex.2015.05.019. Epub 2015 Jun 3. PubMed PMID: 26115582.
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Wired to be WeirdBy Ian McLaughlin & Bo Allen

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