Dr Megan O'Hare is joined by three researchers based at the UK Dementia Research Institute in Cardiff - Dr Sarah Carpanini, Dr Tom Phillips and Dr Megan Torvell to discuss neuroinflammation in neurodegeneration this time using mouse models to examine underlying pathophysiology during brain development and beyond.

Join them to hear about physiological synapse loss that occurs during normal, healthy development of the brain contrasting to pathological synapse loss that occurs in disease states such as Alzheimer's Disease.

Hear more about the role of microglia and the role of the complement cascade as well as the virtues of using mouse models in general for studying an ageing disease.

You can find out more about our panellists, and their work on our website www.dementiaresearcher.nihr.ac.uk. A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcast-neuroinflammation-in-mouse-models/

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Regular host Adam Smith is hosting a 12 hour Dementia Research Live Chatathon - 7th September, 12 hours, over 55 researchers to raise much needed funding for Alzheimer's Research UK. To find out more visit http://www.chatathon.uk

This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support.