In this episode, we provide a comprehensive overview of neurologic disorders, focusing on how nurses assess, diagnose, and manage conditions that affect the central and peripheral nervous systems. We’ll explore the pathophysiology and clinical presentation of key disorders, including infectious conditions like meningitis, autoimmune diseases such as multiple sclerosis and Guillain–Barré syndrome, and neurodegenerative illnesses like Parkinson’s disease. The episode highlights the importance of diagnostic tools—including cerebrospinal fluid (CSF) analysis and neuroimaging—in identifying inflammation, tumors, and neurologic dysfunction. We’ll also emphasize nursing priorities, such as maintaining mobility, supporting respiratory function, and providing patient education for chronic disease management. Finally, we’ll review advanced treatments like plasmapheresis and targeted pharmacologic therapies, underscoring the nurse’s role in stabilizing patients during acute neurologic crises and improving long-term outcomes.