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Neuroverse
By Carolina Soares and Clara LenherrScience
Neuroverse episodes
- 65. Designing Generative Models (with Pierre Glaser)
In today's episode we are joined by Pierre Glaser to discuss designing generative models. Pierre Glaser is a PhD student in Machine Learning at the Gatsby Computational Neuroscience Unit in UCL. He is working with Professor Arthur Gretton on advancing the methodology of flexible generative modelling. We discuss what generative models are (such as ChatGPT, Dall-E), what fitting a probabilistic model to a dataset entails, how physics and neuroscience are used in these models, and many more captivating topics!
Today’s episode was made possible thanks to the support of the Sainsbury Wellcome Public Engagement fund. We would like to thank Sainsbury Welcome Centre (SWC) for the generous grant supporting Science Communication initiatives like these. https://www.sainsburywellcome.org/web/---
We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
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39 min - 64. Tools for Looking into the Brain: Patch-Clamp
We are launching a new mini-series focusing on experimental methods to study the brain! How do we look at and listen to the activity of neurons, populations of neurons, and the whole brain? In this series, we will be exploring the multitude of techniques and recent advances in technologies to study the brain.
To kick of the series, in this episode we discuss patch-clamping, a type of electrophysiological technique that is used to measure the electrical activity and biophysical properties of individual neurons. Drawing on some of our personal experiences, we discuss the uses and challenges of patch-clamp, what we can discover from it, how different variations can offer different insights, and the future of patch-clamp.
---We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
Neuroverse Website
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https://anchor.fm/neuroverse9
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34 min - 63. Protein Dysregulation in Neurodegenerative Disorders (with Dr Estella Newcombe)
In this episode, we are joined by a special guest, Dr. Estella Newcombe, to discuss protein dysregulation in neurodegenerative disorders.
Estella is currently a Marie Sklodowska-Curie Fellow at the University of Copenhagen in the structural biology and NMR laboratory, researching intrinsically disordered proteins in the context of neurodegenerative disorders. Estella holds a Bachelor’s degree in Biotechnology and Chemistry from the University of Queensland and a PhD in Biochemistry and Molecular Biology from the University of Melbourne, where she studied the interactions and structures of proteins in Huntington’s disease. She subsequently worked as a postdoctoral fellow at the Queensland Brain Institute studying the structures of intrinsically disordered proteins. Based on her wide range of experience in the fields of structural protein biology and neuroscience, in this episode we discuss the value of studying human neurodegenerative disorders at the level of protein-protein interactions. We cover what intrinsically disordered proteins are, the relevance of structure-function relationships, and how environmental factors influence protein dysfunction in neurodegeneration.
---
We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
Neuroverse Website
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Podcast directory
https://anchor.fm/neuroverse9
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41 min - 62. What Makes Science Beautiful?
In today’s episode, Carolina and Clara discuss what beautiful science is, and what makes a beautiful experiment? We delve into aesthetics, what is good and beautiful in science, and highlight how these can influence bias in scientific experiments
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We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍Neuroverse Websitehttps://neuroversepod.comPodcast directoryhttps://anchor.fm/neuroverse9Support us!https://ko-fi.com/neuroverseTwitter: @neuroverse_podhttps://twitter.com/neuroverse_pod?s=21&t=KvAEuwGNKFQ9IPKlL7NTEgInstagram: @Neuroverse_podhttps://instagram.com/neuroverse_pod?igshid=YmMyMTA2M2Y=Help us improve our podcast by giving us some feedback!https://forms.gle/PuEMC1BCWXdAqCRQA33 min - 61. Reprogramming Cellular Identity (with Sydney Leaman)
In this episode, we were joined by a special guest, Sydney Leaman, to discuss cellular identity and reprogramming cells in the brain. Sydney holds a BSc and MSc in human genetics as well as a medical degree and is currently completing his PhD in translational neurodevelopment at the MRC Centre for Neurodevelopmental Disorders in King's College London, where he works on reprogramming neuronal identity in the brain. We discuss the motivation behind reprogramming cells, the potential clinical applications for improving regenerative medicine, the challenges that the reprogramming field has faced, the future of reprogramming, and what cellular identity really means. Listen to find out more!
---We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
Neuroverse Website
https://neuroversepod.com
Podcast directory
https://anchor.fm/neuroverse9
Support us!
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Twitter: @neuroverse_pod
https://twitter.com/neuroverse_pod?s=21&t=KvAEuwGNKFQ9IPKlL7NTEg
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https://instagram.com/neuroverse_pod?igshid=YmMyMTA2M2Y=
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45 min - 60. Storing Data in DNA
This week, Carolina & Clara discuss the development of a novel technology- storing data in DNA. As the human population is producing an expontentially growing amount of data every day, it is easy to forget that all of this data also needs to be stored in a physical form. Currently, digital data is largely stored in exabyte centres, large warehouses that require millions of dollars and tons of electricity to maintain. Novel solutions relying on organic materials and biological technologies are therefore necessary for a sustainable approach to data storage. One growing method that is becoming increasingly possible is storing digital binary data in DNA, which is a natural data store that utilises its own unique genetic code. In this episode, we explore the possibility of DNA data storage, the limitations and challenges that need to be overcome, and the future of data.
---
We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
Neuroverse Website
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Podcast directory
https://anchor.fm/neuroverse9
Support us!
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Twitter: @neuroverse_pod
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26 min - 59. Biomimetic and Bioinspired MaterialsIn today’s episode Carolina and Clara discuss biomimetic and bioinspired materials and the challenge with understanding the biological structure of natural materials to then create additional intelligent biological materials that allow us to bridge various challenges. But what about not only mimicking nature? What about creating ‘living’ materials that you can have a bi-directional flow of information? Well.. stay tuned to find out how some scientists where able to control cardiomyocytes (heart muscle cells) with light! Using nature as an inspiration to address problems in building materials for safer architecture that can withstand natural disasters from spider silk and resilin or materials such as chitosan that can change its solubility based on the pH of the environment can be crucial for drug deliver systems. ---We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍Neuroverse Websitehttps://neuroversepod.comPodcast directoryhttps://anchor.fm/neuroverse9Support us!https://ko-fi.com/neuroverseTwitter: @neuroverse_podhttps://twitter.com/neuroverse_pod?s=21&t=KvAEuwGNKFQ9IPKlL7NTEgInstagram: @Neuroverse_podhttps://instagram.com/neuroverse_pod?igshid=YmMyMTA2M2Y=Help us improve our podcast by giving us some feedback!https://forms.gle/PuEMC1BCWXdAqCRQA30 min
- 58. Morphic Resonance
This week, Carolina & Clara discuss the theory of Morphic Resonance. First proposed by Rupert Sheldrake in 1981, the theory of Morphic Resonance accounts for the laws of nature as being habits and a form of collective memory that accumulates across time, rather than ground truth upon which all of nature is built upon. In this episode, we discuss the validity of the theory, evaluate the empirical evidence that exists, and explore how it applies to different areas of knowledge and scales of existence. Listen to find out more!
---
We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
Neuroverse Website
https://neuroversepod.com
Podcast directory
https://anchor.fm/neuroverse9
Support us!
https://ko-fi.com/neuroverse
Twitter: @neuroverse_pod
https://twitter.com/neuroverse_pod?s=21&t=KvAEuwGNKFQ9IPKlL7NTEg
Instagram: @Neuroverse_pod
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Help us improve our podcast by giving us some feedback!
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30 min - 57. Stress, Cortisol and How to Overcome StressorsIn today’s episode Carolina and Clara discuss stress, stressors and the impacts of chronic stress. Stress is a physiological response that aids us in situations of danger, however in our modern society we have created more abstract stressors which may lead to a chronic stress state. The cortisol cycle is a big player in this area. They also discuss mindfulness and other practices to help keep stress at bay!This episode topic was picked by you guys! Do let us know what future topics you’d like to see us do next, you can do so by commenting on our social media.We would also like to announce our new Neuroverse intro music! Kindly provided by TakT, two extremely talented science-artists. You can check out their other music and art-work here: (Music) https://open.spotify.com/artist/6R19JFl7psTx6wNMAMCQos?si=aj_wNBZAT-KIvCb0FthJjg(Art) https://taktarts.com/about-us---We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍Neuroverse Websitehttps://neuroversepod.comPodcast directoryhttps://anchor.fm/neuroverse9Support us!https://ko-fi.com/neuroverseTwitter: @neuroverse_podhttps://twitter.com/neuroverse_pod?s=21&t=KvAEuwGNKFQ9IPKlL7NTEgInstagram: @Neuroverse_podhttps://instagram.com/neuroverse_pod?igshid=YmMyMTA2M2Y=Help us improve our podcast by giving us some feedback!https://forms.gle/PuEMC1BCWXdAqCRQA26 min
- 56. Synapses: Origin & Evolution
In this episode, Carolina & Clara discuss synapses in the brain. What are they? What is their function and importance? Where did they originate from? How are they different across evolutionarily distinct species? They also discuss how recent research in comb jellies has brought back to life an age-old debate between Santiago Ramon y Cajal and Camillo Golgi about the basis of communication in the brain.
---We hope you enjoy the episode! Please feel free to share with your friends and family, it means a lot to us🤍
Neuroverse Website
https://neuroversepod.com
Podcast directory
https://anchor.fm/neuroverse9
Support us!
https://ko-fi.com/neuroverse
Twitter: @neuroverse_pod
https://twitter.com/neuroverse_pod?s=21&t=KvAEuwGNKFQ9IPKlL7NTEg
Instagram: @Neuroverse_pod
https://instagram.com/neuroverse_pod?igshid=YmMyMTA2M2Y=
Help us improve our podcast by giving us some feedback!
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24 min
About Neuroverse
From the publisher's feed
A podcast about neuroscience, philosophy and everything inbetween! Hosted by Clara and Carolina, two young neuroscientists.
For business enquiries please email [email protected]
Support us! https://ko-fi.com/neuroverse
Website: https://neuroversepod.com
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Help us improve our podcast by giving us feedback! https://forms.gle/PuEMC1BCWXdAqCRQA
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