In this episode of the Let's Talk About Kidneys podcast, Dr. Roberto Collazo addresses the development of new treatments for kidney disease that are essential for slowing disease progression, improving patient outcomes, and preventing kidney failure. Throughout his discussion, he will examine various therapeutic options currently available, as well as those expected in the future.

What types of treatments have there been in the past for patients with Chronic Kidney Disease (CKD)?

Dr. Collazo addressed the medications available during the 1990s and early 2000s. He also discussed newly introduced medications aimed at slowing the progression of kidney disease and enhancing patient outcomes.

What are the new types of treatments?

Dr. Collazo discussed several new treatment therapies currently available, which have led to positive outcomes. These treatments include:

· Angiotensin-converting enzyme (ACE) Inhibitors / Angiotensin receptor blockers (ARBs)

· Flozins (also known as sodium-glucose co-transporter 2 or SGLT-2 Inhibitors)

· Non-steroidal mineralocorticoid receptor antagonists (nsMRAs)

· Glucagon-like peptide-1 agonist (GLP-1)

What research has been completed regarding the benefits in treatment of other conditions related to kidney disease?

Dr. Collazo addressed the recent statement issued by the American Heart Association, which acknowledges a new syndrome known as cardio-kidney-metabolic (CKM) syndrome. Cardio-kidney-metabolic (CKM) syndrome is a health condition that impacts the heart, kidneys, and metabolism.

Would you provide me with an example of one of your patients who have benefitted from one of these new treatment therapies?

Dr. Collazo spoke about a recent patient who received a diagnosis of both hypertension and heart disease. He also discussed the measures undertaken to address the patient's condition using new therapies.

How can kidney patients get involved?

Dr. Collazo emphasizes the significance of cultivating a relationship with one's primary care physician and nephrologist. Patients are encouraged to ask about new therapies that may assist in managing or slowing the progression of their condition during their appointments with their physician.

Dr. Collazo concludes the podcast by noting that advancements in nephrology are progressing. New medications and updated therapies are becoming available that will assist in preventing patients from needing dialysis or transplantation.