NewsHour

US Secretary of Defense Pete Hegseth has said an American submarine sank an Iranian warship in the Indian Ocean.

Washington says it's the first time since the Second World War it's used a torpedo to sink an enemy vessel.

Also on the programme: we gauge the scale of the attacks inside Iran by speaking to a resident in Tehran and verifying video footage; and a look at a new AI model, trained on the DNA of over 100,000 species, that is capable of designing new genomes.

(Photo: US Defence Secretary Pete Hegseth speaks during a press briefing at the Pentagon on 2 March. Credit: EPA/Shutterstock)

The Sri Lankan navy says it has rescued 32 people after a distress call from the Iranian IRIS Dena, with around 140 people on board currently missing. We also hear from Iraq's Kurdistan region where reports suggest the US could back the Kurdish armed groups to cross over into Iran in a ground operation.

Also on the programme: the latest from the onflict in the Middle East, with a lineup of who is in the running to take over from Iran's Supreme Leader; the controversial 'Moonies' church that has contravened the law in Japan, and proof that a woman's brain does change during pregnancy.

(Photo: Iranian warship IRIS Dena is seen in the Bay of Bengal during International Fleet Review held at Visakhapatnam in India on 18 February, 2026. Credit: Associated Press)

President Trump says both Iran's leadership and military have been knocked out by US and Israeli attacks on day four of the war. We'll bring you the latest and hear from Lebanon's Deputy Prime Minister as Israel pursues the Iran-backed Hezbollah militia; and how might Gulf states react if Iran continues to attack them?

(An explosion in Tehran, Iran as US/Israeli attacks continue. Credit: EPA/Shutterstock)

As loud explosions continue to be heard across Tehran there are reports that many residents are trying to flee the capital by car while others are stocking up on essential supplies. Israel says it's bombed Iran's presidential office and the US claims to have destroyed command facilities and missile launch sites across the country. Iran has threatened to open the gates of hell as it retaliates.

Also, Leaked photo, hot tub, and Pizzagate - video of Clintons' testimony on Epstein ties released.

And discovering your old painting was actually a masterpiece by Rembrandt!

(Photo: A street in Tehran this morning following a blast at a police station. Credit: Reuters)

President Donald Trump says the US continues to carry out "large-scale combat operations" in Iran to eliminate threats posed by the Iranian regime. As explosions thunder across the Iranian capital, we'll hear from a journalist in Tehran.

Also on the programme: the conflict spreading into Lebanon and across the Gulf, and why one Trump-supporting American commentator believes this war of choice was a mistake.

(Photo: President Donald Trump attends a Medal of Honor ceremony at the White House in Washington, DC. Credit: Reuters)

We hear from Lebanon and head to the Persian Gulf to take a look at the impact on oil prices. Israel's Head of State, President Isaac Herzog speaks to the BBC about his perspective on the conflict.

Also on the programme: we hear about the British allied response to the war as Cyprus remains on high alert and Greece sends military vessels and aircraft to help.

(Photo: Aftermath of an Israeli & US strike in Gandhi Hotel Hospital in Tehran Credit: Majid Asgaripour/West Asia News Agency via Reuters)

Israel has said it has dealt a "severe blow" to Iran's command and control centres as it continues to strike the country. Iran's retaliations have led to casualties across the region. In the meantime, President Trump has said he is open to talking to Iran's new interim leaders.

We hear the latest from the ground in Tehran, talk to an Israeli MP and an economist about the impact on oil prices as shipping comes to a standstil in the Strait of Hormuz.

(Photo: a supporter of deceased Iranian Supreme Leader Ayatollah Ali Khameini holds its picture at a rally in Lebanon. Credit: EPA/Shutterstock)

Iran's interim leadership council has been named following the death of its Supreme Leader Ayatollah Ali Khamenei in a US-Israel attack. In Israel nine people have been killed by retaliatory strikes from Tehran.

(Photo: Smoke rises following an explosion, after Israel and the U.S. launched strikes on Iran, in Tehran, Iran, March 1, 2026. CREDIT: Majid Asgaripour/WANA (West Asia News Agency) via REUTERS)

US President Donald Trump says that Iran's supreme leader, Ayatollah Ali Khamenei, is dead following after a day of U.S. and Israeli military strikes. Iranian state media denies Mr Khamenei is dead. We bring you the latest political and diplomatic developments from across the world and from inside the country.

(Photo: People walk near a mural featuring images of Iran's Supreme Leader Ayatollah Ali Khamenei in Tehran. Credit: Majid Asgaripour/Reuters).

Reuters )

The US and Israel have carried out a joint attack on Iran. President Donald Trump confirms the start of a 'major combat operation,' and calls for regime change. We bring you reaction from neighbouring countries in the Middle East and the Gulf. We also hear from an Iranian resident in the capital Tehran, and views from Washington and Israel.

(Photo: Smoke rises following an explosion in Tehran, after Israel launched an attack, February 28, 2026. Credit: Reuters)