Next-generation sequencing is a catchall term for new, high-throughput technologies that allow rapid sequencing of a full genome. It can be used to sequence a patient’s DNA in diagnosing a genetic disorder or characterizing a cancer, but it can also be used to sequence the genome of a pathogenic bacteria, virus, fungi, or parasites. In this JAMA clinical review podcast, we talk with authors Marta Gwinn, MD, MPH, and Gregory L. Armstrong, MD, from the CDC, about how next-generation sequencing of infectious pathogens is being implemented in clinical practice and in public health surveillance for infectious disease. Related Article(s):  Next-Generation Sequencing of Infectious Pathogens Podcast originally published 2/14/19.

Next Generation Sequencing of Infectious Pathogens in Public Health and Clinical Practice (Repost)

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Respiratory syncytial virus (RSV) is a common infection that may cause severe illness in infants, young children, and older adults. Kathleen A. Linder, MD, of the VA Ann Arbor Healthcare System, discusses therapies to prevent severe RSV illness with JAMA Deputy Editor Kristin Walter, MD, MS.  Related Content:  Therapies to Decrease Severe Respiratory Syncytial Virus Illness Assessing the Real-World Effectiveness of Immunizations for Respiratory Syncytial Virus 

Treatments to Decrease Severe Respiratory Syncytial Virus (RSV) Illness

Chronic pruritus, defined as itch lasting more than 6 weeks, affects approximately 22% of people in their lifetime. In this JAMA clinical review podcast, dermatologist Daniel C. Butler, MD, from the University of Arizona College of Medicine, joins JAMA Deputy Editor Mary McGrae McDermott, MD, to discuss evaluation and management of chronic pruritus.  Related Content:  Chronic Pruritus 

Chronic Pruritus

The Federal Trade Commission’s (FTC) oversight role in the pharmaceutical market is critical to the health of patients and the health care system. Aaron Kesselheim, MD, JD, MPH, and JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discuss the FTC’s policies and legal actions related to alleged misconduct, consolidation, and anticompetitive behavior in the pharmaceutical market.  Related Content:  Federal Trade Commission Actions on Prescription Drugs, 2000-2022 

The Federal Trade Commission’s Role in the Oversight of Drug Companies

Do text messages with or without financial incentives increase weight loss in men with obesity? Pat Hoddinott, MB, BS, PhD, of Stirling University talks with JAMA Deputy Editor Mary McGrae McDermott, MD, about the results of a randomized clinical trial that tested whether financial incentives combined with text messaging could help men with obesity lose weight.  Related Content:  Text Messages With Financial Incentives for Men With Obesity 

Financial Incentives for Weight Loss in Men With Obesity

Over the last several years there has been a proliferation of assistance animals in health care, including service animals, therapy animals, and emotional support animals. Lisa I. Iezzoni, MD, MSc, of Harvard Medical School and the Health Policy Research Center at Massachusetts General Hospital, joins JAMA Senior Editor Karen E. Lasser, MD, MPH, to discuss service animals in health care settings.  Related Content:  Service Animals in Health Care Settings 

Next Generation Sequencing of Infectious Pathogens in Public Health and Clinical Practice (Repost)

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