NIH Collaboratory

Dr. Sean Tunis and Ellen Tambor discuss with moderator Dr. Kevin Weinfurt their findings on clinician attitudes towards research participation, and how and when to best engage them. They describe the need for involving clinicians in the planning of study design, and in closing feedback loops after studies are completed, in order to build clinicians’ trust that research does lead to quality improvement for their patients.

Dr. Andrew Faucett of Geisinger describes the considerations for the return of genomic results to patients.

Drs. Richard Platt and Christopher Granger speak with moderator Dr. Adrian Hernandez about the IMPACT-AFib atrial fibrillation trial and the role of the FDA’s Sentinel Inititative. In this trial, researchers used Sentinel pharmacy data to find eligible patients with at least one oral anticoagulation prescription fill, and the speakers describe how the platform provided them with an efficient and cost-effective way to access the data of over 80,000 potential participants.

Dr. Harlan Krumholz of Yale University Medical Center speaks with the NIH Collaboratory’s Dr. Adrian Hernandez about the ways preprint servers can help accelerate scientific progress through greater access to research results.

Dr. Greg Simon, principal investigator of the Suicide Prevention Outreach Trial (SPOT), and Susan Ellenberg, a member of the Collaboratory Regulatory/Ethics Core, speak with moderator Dr. Adrian Hernandez about the factors that determine the need for a Data and Safety Monitoring Board (DSMB) in pragmatic trials.

Drs. Adrian Hernandez and Kevin Weinfurt, two NIH Collaboratory Co-PIs and podcast moderators, discuss their predictions and hopes for the NIH Collaboratory in the next year.

Dr. Greg Simon of the Kaiser Permanente Washington Health Research Institute speaks with the NIH Collaboratory’s Dr. Lesley Curtis about the integration of machine learning into suicide prevention.

Dr. Karen DeSalvo, former acting Assistant Secretary for Health and Human Services, speaks with the NIH Collaboratory’s Dr. Kevin Weinfurt about the factors other than healthcare systems than impact the health of our communities.