In the immune system, white blood cells help protect the body from viruses and bacteria. A subset known as macrophages offer great promise for cancer treatment. We are joined by Kolade Adebowale, a postdoctoral fellow at the Harvard John A. Paulson School of Engineering and Applied Sciences to hear about his macrophage studies, how they might be made more effective, and why we should be optimistic about the future of cancer treatment.

Since the discovery of incomplete dinosaur skeletons in the early 1800s, the collective knowledge about these creatures that roamed the Earth millions of years ago has grown dramatically. We are joined by Greg Erickson, a professor of anatomy and vertebrate paleobiology at Florida State University and curator at FSU's Biological Science Museum who shares how new Gorgosaurus discoveries impact what we know about ancient eating patterns, how he aged the famous Tyrannosaurus rex Sue, and his role in uncovering a lost world of arctic creatures that is changing what we know about dinosaurs.      

Light catches the imagination and raises questions about phenomena such as rainbows or why the sky is blue from an early age. We are joined by Franklin Dollar, professor of physics and astronomy and associate dean of graduate studies in the School of Physical Sciences at University of California, Irvine to hear about how he uses extreme ultraviolet light and lasers to reproduce and study the plasma states and particle acceleration that occur in the most extreme corners of the universe.  

The U.S. National Science Foundation's Center for Computer Assisted Synthesis is developing data science tools and computational workflows that aim to shape the future of synthetic chemistry. We are joined by Gabe Gomes, assistant professor of chemistry and chemical engineering at Carnegie Mellon University, to hear about the work being done at the facility and the revolutionary new tool his team has developed, Coscientist.

From the Viking age to a Cold War military installation revealing insights into the ice age, advances in artificial intelligence, and looks at black holes and gravitational waves in the depths of space, these are just some of the stunning findings produced by U.S. National Science Foundation-supported researchers in 2023. As we start a new year, we're looking back at some memorable moments from the past year's shows.

Humans have always looked up to the sky and wondered about the stars and what life may be out there. Astronomers are using tools such as the U.S. National Science Foundation’s Green Bank Observatory and the Karl G. Jansky Very Large Array to search for radio waves, technosignatures sent from distant stars. David DeBoer, a research astronomer at the University of California, Berkeley joins to explain how Breakthrough Listen is leading this effort and how the Collaboration for Astronomy Signal Processing and Electronics Research is advancing the technology behind it.

Blue whales are the largest animals to ever inhabit the planet and were hunted to near extinction in the era of commercial whaling. Since the 1960's, these giants have been protected but continue to be considered endangered and are seldom seen. Kate Stafford, an associate professor and bio-acoustician at Oregon State University's Marine Mammal Institute, joins today to explain how a film brought her to the Republic of Seychelles to locate blue whales using their vocalizations, share insights into whale song and explain how she hears climate change.

The U.S. National Science Foundation's Graduate Research Fellowship Program (GRFP) has helped ensure the quality, vitality and diversity of the scientific and engineering workforce by recognizing and supporting outstanding graduate students since 1952. Kyle Johnson, a doctoral student at the University of Washington, joins us to talk about his work with robotics, his GRFP experience and how he inspires the next generation.

The ubiquity of plastic materials in modern life has meant that plastic debris can be found everywhere. A subset of these environmental contaminates, smaller than a sesame seed, are called microplastics, and an even smaller subset of those are called nanoplastics. We are joined by Lauren Pincus, an environmental chemist and post-doctoral fellow at Princeton University, to learn about plastic degradation, how it interacts with inorganic materials in the environment and what we might do to help prevent it.

The U.S. National Science Foundation has invested over half a billion dollars to establish the National AI Research Institutes. We are joined by D.K. Panda, from the AI Institute for Intelligent Cyberinfrastructure with Computational Learning in the Environment; Giovanni Vigna, from the AI Institute for Agent-based Cyber Threat Intelligence and Operation; Yiran Chen, from the AI Institute for Edge Computing Leveraging Next Generation Networks; Ness Shroff, from the AI institute for Future Edge Networks and Distributed Intelligence; and Tess DeBlanc-Knowles, staff associate for technology policy and strategy in NSF's Directorate for Technology, Innovation and Partnerships, to hear how these institutes will drive cutting-edge innovations in AI and how society will benefit from this research.