One Man's Family debuted as a radio series on April 29, 1932 in Los Angeles, Seattle and San Francisco, moving to the full West Coast
rel="noopener noreferrer">NBC network the following month, sponsored by Snowdrift and Wesson Oil. On May 17, 1933, it expanded to the full coast-to-coast NBC network as the first West Coast show heard regularly on the East Coast.
The show was broadcast as a weekly half-hour series (1933-1950) [sustained by Standard Brands from 1935 through 1949], then shifted to daily 15-minute installments, initially originating from the studios of San Francisco radio station KPO, NBC's flagship station for the West Coast, eventually moving to Los Angeles.