Mark and Andrew talk about MMJ, prescription meds, Andrew's health history, humanity's future needs, nuclear weapons, atomic stalemate, robot armies, George Gilder, the pony express, email, long distance calling, the Internet's destabilizing force, the NSA, archiving information for the future, the Svalbard Global Seed Vault, Russia's DNA archive, the commodification of computers, leap-frogging old tech, Third World Internet use, the Taj Hotel terrorist attack in Mumbai, Google Earth, sugar, circadian rhythms, artificial adaptations to an artificial world, new forms of social engagement, Facebook, personal brand, Marshall McLuhan, being famous, new modes of governance, color-changing light, and earthing.