'Why we do What we do in Cardiology'

PAD: Peripheral Arterial Disease Updates from 2023

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Key Points of Endovascular Procedures and Devices in 2023:

FDA Actions:

  • Lifted restrictions on paclitaxel-coated balloons and stents for PAD after updated data showed no increased mortality risk.
  • Approved coverage of carotid artery stenting for Medicare beneficiaries with severe stenosis.
  • Approved the LimFlow device for diverting blood flow in severe CLTI patients, offering limb salvage hope.
  • Approved the Paradise and Symplicity Spyral systems as the first renal denervation devices in the US.

    • CLTI Debate:

    • Conflicting data from the BEST-CLI (surgery preferred) and BASIL-2 (endovascular preferred) trials emphasize patient-specific treatment decisions.

      • Other Developments:

      • LIFE-BTK trial showed promising results for a new resorbable scaffold in below-the-knee interventions.
      • PEERLESS II, HI-PEITHO, and STORM-PE trials are investigating advanced therapies for pulmonary embolism.

        • Future Outlook:

        • The endovascular field is poised for continued innovation with new technologies and ongoing research.
        • There is a need for operator training and reimbursement clarity for novel techniques like renal denervation.
        • Upcoming PE trials are expected to provide level 1 evidence for improved treatment options.


          • ...more
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          'Why we do What we do in Cardiology'By Bishnu Subedi

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