In this episode, radiation oncologists Malcolm Mattes, MD, from Rutgers Cancer Institute, and Jolinta Lin, MD, from Emory Winship Cancer Institute, will provide a broad overview of the use of radiation therapy for symptom relief in patients with metastatic cancer. They cover treatments for bone metastases, brain metastases, spinal cord compression, airway obstruction, vena cava obstruction, malignant wounds, and bleeding. They also discuss use of radiation for oligometastatic cancer that is not symptomatic.