Hi, I am Marmee Regine, your host in Pandemic Podcast Coronavirus.
Today we are now in the 5th episode where we will discuss the most anticipated vaccine. That is why the episode title is, "To vaccinate or not to vaccinate." There is always a dilemma that humans like us are facing every day. It is a reflection of the famous lines in literature, "To be or not to be." It is a question on which path to take when you are on the crossroads of life. "To be, or not to be" is the opening phrase by Prince Hamlet in Act 3, scene 1 of William Shakespeare's play Hamlet. It is all about life and death: "To be or not to be" has a meaning about life and death. "To live or not to live," which means "To live or die." Hamlet discusses how painful and miserable to live a life back then and how death, such as suicide, is the solution to end such misery. And fast forward to today, many people living in these uncertain times of the pandemic are having difficult times; that is why those who tested positive in China committed suicide. I mentioned that in passing from my previous podcast episode #2 on viral load. Isn't it ironic that history repeats itself even after several centuries?
Moving on, this is the first part of my podcast episode on the topic of vaccines. In this episode, let us start this discussion on the historical notes that researchers did in the past until the present, which is the so-called self-experimentation of their study drug or vaccine along with some of their volunteer friends. An article regarding this matter was published entitled, Self-Experimentation in the Time of COVID-19. It was published in the online magazine, The Scientist which was well researched by the writer, Amanda Heidt, who is in her second master's in science communication at the University of California, Santa Cruz.
Link: https://www.the-scientist.com/author/amanda-heidt-4941
I will share the link on my Patreon page. Let us go into a brief flashback in time. In the olden days, an infectious disease expert in the US Public Health Service, by the name of Joseph Goldberger, was given the responsibility in 1914 to study the pellagra's causation. Pellagra is a skin disease with classic symptoms of dermatitis, diarrhea, dementia, and death. Most of the scientist believed those times believed that it was due to a germ. However, Goldberger's theory is that pellagra was due to a nutritional deficiency. Did you know that Joseph Goldberger, his wife, and some volunteers joined them to inject themselves the blood of pellagra victims and an intake of a pill form containing the feces and urine of patients? Ewww, a human guinea pig? Goldberger repeated this experimentation in other cities, and before he died of cancer in 1929, his research work landed him four Nobel Prize nominations. Wow, the saying here is applicable, "You reap what you sow."
In other famous examples, a virologist from the University of Pittsburgh named Jonas Salk, who initially tested the polio vaccine to himself and his children in the year 1952 before giving it to other volunteer subjects. You heard it right that Jonas Salk tested his original polio vaccine on both himself and his children ahead of widespread trials. Another example was from a married Russian couple, Marina Voroshilova and Mikhail Chumakov, who were considered polio experts. They also self-administered in 1959 a potential vaccine before letting their three sons have an intake of those sugar cubes laced instilled with a weakened poliovirus. After a lengthy argument in what form of drug administration to give patients, they agreed on the oral intake of the vaccine using live poliovirus. Later on, in 1994, the World Health Organization declared polio disease eradicated in the Western Hemisphere.
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