Patients with autoimmune disease have faced some distinct challenges during the COVID-19 pandemic. These challenges include tough decisions about whether to stop their immunosuppressant therapy and difficulties refilling their regular prescriptions for hydroxychloroquine. Dr. Tracy Frech, director of the Systemic Sclerosis clinic at the University of Utah, describes how she's supporting her patients during this difficult time. She also describes her research collaboration with clinical laboratorians and other academic colleagues to find answers to key questions that are important for this patient population.