PB With J's

ALS - Amyotrophic Lateral Sclerosis - has gained a lot of notoriety and attention in recent years. But aside from the ice bucket challenge and Lou Gherig's name, how much do we really know about this deadly neurological disease?

In this episode we'll dive into the scientific thoughts and theories regarding ALS: how does it develop? what cellular pathologies exist? can we develop a more effective treatment? Plus, we'll hear about Jacob's aspirations for space and Joseph's complete and utter lack of architectural aptitude.

So let's get started-Episode 7, ALS

In this podcast we hope to give you a good run down on one of the most researched topics in the neuroscientific field today: Alzheimer's Disease (AD). It's one of our longer episodes, seeing as the topic is so big, but hang with us as we navigate through the complex science and sociology surrounding this debilitating degenerative disease.

It's one lots of people have heard of, but get ready to dive into how it works.

Huntington's Disease exists with an almost mysterious heir about it in media and culture - it's dangerous and deadly, but what truly is it?

It's been described as a disease that exhibits the physical manifestations of Parkinson's and ALS to go along with many of the behavioral and emotional manifestations of Alzheimer's. In this episode, we explore the significance of such a powerfully influential and impactful disease, discussing how it works and where we are in our understanding of it.

The final and third installation of our Neuro Basics suite, we've finally arrived at Neuroanatomy. Here we'll explore the basic names and structures that allow your brain to function, ultimately allowing you to be you.

You hear all the time in the media "they're left brain dominant" or "this function happens in the back of your brain" - but what do claims like these mean? We'll explore those questions and more in this episode, painting a sort of neuroantomical map as we get ready to dive into future episodes.

The second installment of the "Cells and Ions" basics. In this episode we focus on ions and ion channels. What even are ions? How do they affect Brain Physiology and functioning? What the heck is an action potential?

In this episode we'll explore all these questions, hopefully clearing the air a bit on how neurons communicate and what role ions and electricity play in that communication.

Before we dive into the mystery of various neurological diseases and disorders, we first need some basic vocabulary - how to ions and channels result in an action potential firing and propagating down a neuron?

If that question sounded a bit jargony, well, it is. But for this episode and the next we're working to unpack that jargon and lay the foundation for future episodes.

So without further ado - cells and ions, here we go!

PB With J's (Physiology of the Brain With Jacob and Joseph) is a new Podcast from a couple college kids hoping to connect science in society in a unique, fun, and engaging manner. It's the start of a scientific adventure, and after a lot of hard work and planning, we're finally here with one thing to say: What's Up World??