In this episode, we break down the key medications used to treat male reproductive disorders, focusing on erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and prostate cancer. We’ll explore PDE-5 inhibitors for ED, reviewing their mechanism of action, administration guidelines, and serious adverse effects such as priapism. For BPH, we’ll examine 5α-Reductase Inhibitors and α1-Receptor Blockers, explaining how they reduce prostate size and relax smooth muscle to improve urinary flow—alongside nursing considerations for orthostatic hypotension and patient safety. Finally, we’ll discuss Androgen Deprivation Therapy and chemotherapy used in prostate cancer management, emphasizing drug mechanisms, hormone regulation, and essential patient education for managing long-term side effects. This episode gives nurses a complete understanding of men’s health pharmacology and safe medication practices.