PHEMCAST

PHEMCAST

By Tim Nutbeam and Clare BosankoMedicine
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PHEMCAST episodes

  • Altitude

    From: https://www.bbc.co.uk/news/uk-wales-46441129

    From: https://www.ultimatekilimanjaro.com/blog/should-i-use-supplemental-oxygen-on-kilimanjaro/

    A portable hyperbaric chamber (Gamow bag)
    From: https://litfl.com/hypothermia/
    Classic stretcher technique
    Improvised rucksack stretcher technique

    Want to know more?

    This is one of the organisations Lucy mentions: British Exploring

    And this is the Global Health MSc

    The Wilderness Society Guidelines are available here.

    This is the link to the Wilderness Medical Society.

    Consensus statement from the UIAA on People with Pre-Existing Conditions Going to the Mountains, and their website for more useful resources.

    Li Y, Zhang Y, Zhang Y. Research advances in pathogenesis and prophylactic measures of acute high altitude illness. Respiratory Medicine. 2018; 145: 145-152. https://doi.org/10.1016/j.rmed.2018.11.004

    The Faculty of Prehospital Care have also published guidance on the Medical Provision for Wilderness Medicine. Thanks to Dave Hillebrandt for sharing this with us.

    51 min
  • Drowning

    Some facts

    Drowning is important: 1,000 people drown every day, 2 every 3 minutes, 41 per hour. It is the world’s 3rd leading cause of accidental death: 3.6 million people over 10 years.

    Disease of youth

    • 64% < 30 years old
    • 43% < 15 years old
    • 25% < 5 years old

    Male: female ratio 2:1

    In 40%, alcohol is on board

    4 stages of Immersion associated with particular risk in drowning

    Initial Responses/Sudden Death (first 3-5 min)

    • Skin cooling

    Short-Term Responses (5-30 min)

    • Superficial Nerve and Muscle Cooling

    Long-Term Responses (30 min +)

    • Cooling of deep tissues

    Post-immersion (during rescue)

    • Collapse of arterial pressure
    • Continued cooling
    Fresh versus salt water drowning

    Lethal aspiration of salt water 22ml/kg (approx 1.5 litre), fresh water 44ml/kg

    Be aware that drowning can take up to 4 hours – observe and watch for 6!

    Prognostication

    Better outcomes:

    • Rescued and BLS commenced < 5-10 min
    • Children
    • Those who have not aspirated
    • Water temperature < 10 oC, core body temperature 33-35 oC
    • Neurologically intact on arrival at hospital
    • Minimum blood pH > 7.1, blood glucose < 11.2mmol/L
    • ROSC on scene
    • Spontaneous ventilation in ED

    Worse prognosis

    • Risk of death or severe neurological impairment after hospital discharge is reported to be nearly 100% when the duration of submersion exceeds 25 min
    • Following 30 mins resuscitation, if no signs of life, resuscitation is futile -> stop

    It is important to remember that casualties who have entered water sometimes have access to a “bubble” of air – particularly if they had entered the water following a boating incident or were in a car at the point they entered the water. In these circumstances it is impossible to judge the point at which submersion has occurred. 

    What about cold water???

    This is a regular point of discussion and concern. Water temperature is a key determinant: icy versus not. In the UK sea water is very unlikely to be icy or cold enough – however, small areas of water may well be, particularly in the winter months. 

    References
    • Szpilman D, Bierens JJ, Handley AJ, Orlowski JP (2012) Drowning. New Engl J Med. 366: 2102–10. 
    • Tipton & Golden (2011). Decision making guide for immersion incidents involving total (head under) submersion. Resuscitation. 82: 819-824.
    • Golden & Hervey, 1981 
    • Oakley & Pethybridge, 1997
    • Tipton 2016
    • Bierens 2014. Handbook of Drowning.

    51 min
  • Episode 36: COVID-19

    https://phemcast.co.uk/wp-content/uploads/2020/05/covid-02-05-2020-18.41.mp3

    Case definition

    Current case definition for COVID-19 can be accessed here.

    Risk stratification

    This is the Emergency Medicine Specialty guide we discussed in the podcast, which includes use of the NEWS and 40 step test (edit: since recording the podcast yesterday (!) we’ve been made aware of the Sit to Stand test). Here is a review of both if you’d like to read more.

    PPE

    As at May 1st, the advice from PHE is ‘There is currently sustained transmission of COVID-19 throughout the UK as defined by the four nations Public Health experts, therefore there is an increased likelihood of any patient having coronavirus infection. Therefore, whilst in this phase all patient contacts require level 2 PPE in accordance with Table 4‘: T4_poster_Recommended_PPE_additional_considerations_of_COVID-19

    Level 2:
    • disposable gloves
    • disposable apron
    • fluid repellent surgical mask
    • eye protection (if risk of splashing)
    • Level 3:
      • disposable gloves
      • fluid repellent coveralls/long sleeved apron/gown
      • FFP3* or powered respirator hood
      • eye protection
      • *Where an FFP3 mask with a non-shrouded valve is worn, it should be accompanied by a full-face visor. If a visor is not available, then a risk assessment should be carried out regarding the risk of splash to the valve. If a large splash (as opposed to droplets) does occur, then the FFP3 mask should be replaced immediately.

        There are a number of PHE PPE videos available, this is the one describing donning and doffing Level 2.

        From PHE Guidance for ambulance trusts: Where AGPs such as intubation are performed, PPE guidance set out for AGPs (section 8.1) should be followed (disposable fluid repellent coveralls may be used in place of long-sleeved disposable gowns). For any direct patient care of patient known to meet the case definition for a possible case, plastic apron, FRSMs, eye protection and gloves should be used. Where it is impractical to ascertain case status of individual patients prior to care, use of PPE including aprons, gloves, FRSM and eye protection should be subject to risk assessment according to local context. PPE is not required for ambulance drivers of a vehicle with a bulkhead and those otherwise able to maintain social distancing of 2 metres. If the vehicle does not have a bulkhead then use of a FRSM is indicated for the driver (additional PPE would be as for other staff if providing direct care).

        For the coverall-type Level 3 PPE most commonly being used by ambulance clinicians, have a look at these two guidelines on donning and doffing.

        Aerosol generating procedures

        Reference available here.

        Aerosols are produced when an air current moves across the surface of a film of liquid; the greater the force of the air the smaller the particles that are produced. Aerosol generating procedures (AGPs) are defined as any medical and patient care procedure that results in the production of airborne particles (aerosols). AGPs can produce airborne particles <5 micrometres (μm) in size which can remain suspended in the air, travel over a distance and may cause infection if they are inhaled. Therefore AGPs create the potential for airborne transmission of infections that may otherwise only be transmissible by the droplet route.

        The most recent assessment by WHO (2014) states that there is only consistent evidence that there is an increased risk of transmission for the following procedures: tracheal intubation, tracheotomy procedure, non-invasive ventilation, and manual ventilation before intubation as AGPs. This evaluation is based on a systematic review by Tran et al. whose review included 10 studies (5 case-control; 5 cohort), all of which investigated transmission of SARS from patients to healthcare workers in intensive care or other healthcare settings during the 2002-2003 SARS outbreaks.

        Cardiac arrest
        From PHE:

        First person attending scene

        • In order to minimise any delay attending a time critical cardiac arrest, it is acceptable for the first person to enter the scene wearing level 2 PPE (fluid repellent surgical mask, apron, gloves and eye protection). Where trained and equipped to use level 3 PPE, this may be used where it will not cause a delay
        • commence resuscitation where this is indicated by local clinical guidance. If resuscitation is not commenced, or is terminated before the arrival of other resources, provide an early sitrep to reduce the number of responders who need to enter the scene
        • do not place your face near the patient to assess breathing
        • where available, place a surgical mask or oxygen mask on the patients face
        • commence chest compressions, attach the defibrillator and defibrillate if indicated. None of these tasks are considered aerosol generating procedures (AGPs)
        • do not progress to airway management or ventilation
        • if not already available on-scene, request back up from a level 3 PPE trained response
        • Subsequent attendance at scene of responder(s) trained and equipped to use level 3 PPE

          • don level 3 PPE
          • enter scene and determine whether the resuscitation should be continued according to local clinical guidance.
          • if resuscitation is to be continued, take over patient management from any responder wearing level 2 PPE
          • all responders wearing level 2 PPE are to leave the scene (more than 2m away from the patient) prior to the commencement of any airway management, ventilation or other AGPs. Responders may later re-enter if trained and equipped to wear level 3 PPE
          • level 3 PPE responders to continue the resuscitation, including airway management and ventilation
          • Anyone who is not trained or does not have access to level 3 PPE must then withdraw from the scene.

            From the Resuscitation Council:

            Click here for more from the Resus Council on COVID-19.

            Just before you go … something to make you smile! (thankfully the music department at Plymouth Uni have got the tech to make me sound like I can actually sing!!!)

            References

            For more on the growing evidence base around COVID-19, please have a read of this blog from our colleague, and Defence Professor of Emergency Medicine, Jason Smith.

            World Health Organization. Infection prevention and control of epidemic and pandemic-prone acute respiratory infections in health care. WHO guidelines. https://www.who.int/csr/bioriskreduction/infection_control/publication/en/ (2014).

            Tran K, Cimon K, Severn M, et al. Aerosol generating procedures (AGP) and risk of transmission of acute respiratory diseases (ARD): A systematic review. PloS One 2012; 7. Conference Abstract.

            https://www.gov.uk/government/publications/covid-19-guidance-for-ambulance-trusts/covid-19-guidance-for-ambulance-trusts#patient-assessment

            Tim Cook PPE review: https://onlinelibrary.wiley.com/doi/epdf/10.1111/anae.15071

            Health Service Journal: Exclusive: deaths of NHS staff from covid-19 analysed

            Considering transmission from staff uniforms:

            Infection Control and Hospital Epidemiology. Volume 31, Issue 5 May 2010 , pp. 560-561. Coronavirus Survival on Healthcare Personal Protective Equipment. Lisa Casanova (a1), William A. Rutala (a2), David J. Weber (a2) and Mark D. Sobsey (a1). DOI: https://doi.org/10.1086/652452

            PLoS One. 2011; 6(11): e27932. Survival of Influenza A(H1N1) on Materials Found in Households: Implications for Infection Control. Jane S. Greatorex, 1  Paul Digard, 2  Martin D. Curran, 1  Robert Moynihan, 2  Harrison Wensley, 2  Tim Wreghitt, 1  Harsha Varsani, 1  Fayna Garcia, 1  Joanne Enstone, 3  and Jonathan S. Nguyen-Van-Tam 3 , 4 , * https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222642/

            Acute myocardial injury in COVID

            https://www.nice.org.uk/guidance/ng171/resources/acute-myocardial-injury-algorithm-pdf-8717541373

            https://www.nice.org.uk/guidance/ng171/chapter/3-Diagnosing-acute-myocardial-injury-in-patients-with-suspected-or-confirmed-COVID-19

            See also: Clinical guide for the management of critical care for adults with COVID-19 during the coronavirus pandemic

            1 hr 3 min
          • Episode 35: The collapsed infant

            https://phemcast.co.uk/wp-content/uploads/2019/09/infant-with-fluid-clarification.mp3

            A: Optimal airway position for infants

            Note how a rolled towel is placed under the baby’s shoulders to allow space for the occiput and avoid flexion of the neck and airway.

            From: https://www.jems.com/2017/02/28/an-overview-of-ems-pediatric-airway-management/

            ‘B’ assessment

            Video links to examples of children with signs of respiratory distress:

            • Stridor
            • Grunting
            • Increased work of breathing
            • ‘D’ assessment

              Example video showing a bulging fontanelle (excuse the slightly cheesy style!)

              From: http://casemed.case.edu/clerkships/neurology/NeurLrngObjectives/Floppy%20Baby.htm

              Non accidental injury

              Sadly, NAI in under 2’s causes more than 10% of serious injuries to children.

              Stigmata of possible NAI include:

              • Bruising on the cheeks, neck, genitals, buttocks and back
              • Pattern bruising from an implement including fingertip bruising
              • Burns to hands, legs, feet and buttocks
              • Subconjunctival haemorrhage
              • Epistaxis in infants
              • Example of subconjunctival haemorrhage:

                From: http://champprogram.com/question/3a.shtml

                2017 NICE guidance: When to suspect maltreatment in under 18s. 

                Sepsis

                Click for UK Sepsis Trust guidance for different clinical settings. Scroll down for the Screening and Action tool for under 5s for prehospital care and ambulance services.

                References regarding IM benzylpenicillin that Tim mentions:

                • Harnden A. Parenteral penicillin for children with meningococcal disease before hospital admission: case-control study. BMJ. 2006 Jun 3;332(7553):1295–8.
                • Hahné SJM, Charlett A, Purcell B, Samuelsson S, Camaroni I, Ehrhard I, et al. Effectiveness of antibiotics given before admission in reducing mortality from meningococcal disease: systematic review. BMJ. 2006 Jun 3;332(7553):1299–303.
                • Sörensen HT, Nielsen GL, Schönheyder HC, Steffensen FH, Hansen I, Sabroe S, Dahlerup JF, Hamburger H, Olsen J: Outcome of pre-hospital antibiotic treatment of meningococcal disease. J Clin Epidemiol 1998, 51:717–721.
                • Drug calculator

                  Example of a paediatric drug calculator from WATCh.

                   

                  29 min
                • Episode 34: Back pain

                  https://phemcast.co.uk/wp-content/uploads/2019/07/back-pain_final-12072019-17.13.mp3

                  So, where is the Cauda Equina?

                  From Core EM

                  How does a herniated disc cause CES?

                  This fab infographic summarising the key points about the CES guidance was produced by @DrLindaDykes and @saspist.

                  Here is the full guideline from The Society of British Neurological Surgeons and The British Association of Spinal Surgeons.

                  NICE guidance on Low back pain and sciatica in over 16s: assessment and management

                  NICE clinical knowledge summary on Cauda Equina Syndrome red flags.

                  Thinking about posture:

                  28 min
                • Episode 33: Psychosomatic Illness

                  https://phemcast.co.uk/wp-content/uploads/2019/03/f-psychosomatic-final-31032019-08.27.mp3

                  Many thanks to Suzanne O’Sullivan for her time in putting this podcast together. Her excellent books “It’s all in your head” and “Brainstorm” are well worth a read.

                   

                  It is certainly one of the PHEMcast recordings which is going to change my own practice the most.

                   

                  We can all find these patient’s challenging to look after – we often fail to communicate effectively and meaningfully. This is understandable as so much of our training and experience is based around the treatment of the physical condition.

                   

                  The key things I took away from this interview were:

                   

                  • A vast majority of patients with psychosomatic symptoms have no control over their symptoms: even when they are made aware that there is no physical / pathological cause
                  • By attributing psychosomatic symptoms to physical causes we are doing our patients a huge disservice
                  • The sooner a psychosomatic cause for symptoms is identified and discussed with the patient the more likely they are to make a recovery
                  • The misdiagnosis rate of a psychosomatic cause is low
                  • There are several features of dissociative seizures that can help us distinguish them from true epileptic seizures
                  • ‘Malingering’ (pretending to be unwell for gain) is extremely rare
                  •  

                    There are a huge number of terms to describe psychosomatic illness – some of which are not useful. A common nomenclature here will help communication between both health care professionals and our patients.

                     

                    Psychosomatic: a physical illness or other condition) caused or aggravated by a mental factor such as internal conflict or stress.

                     

                    Non-epileptic seizures  = dissociative seizures.

                     

                    The terms ‘functional’ and ‘supratentorial’ are best avoided!

                     

                    As always please let us know your thoughts!

                     

                    32 min
                  • Episode 32: Ketamine

                     

                    https://phemcast.co.uk/wp-content/uploads/2019/03/ketfinal.mp3

                     

                     

                    Huge thanks to the team at World Extreme Medicine and WEM Cast for sharing the interview with Richard Harris.

                     

                     

                     

                    Dosing

                    These are a guide only, each patient will need a bespoke approach depending on their pre-existing condition, degree of cardiovascular compromise, conscious level and drugs already administered. Clearly you also need to remain within your scope of practice and the guidelines for your organisation.

                    • For analgesia (IV/IO): 0.1 – 0.5mg/kg
                    • For analgesia (IN): 3mg/kg
                    • For sedation (IV/IO): 1mg/kg
                    • For sedation (IM): 4-5mg/kg
                    • For anaesthesia (IV): 1-2mg/kg
                    • Click here for an example of how ketamine can affect patients.

                      Know the concentration you carry!

                      Click here for an example of what can occur if the incorrect concentration of ketamine is administered.

                      References
                      1. The PICHFORK (Pain in Children Fentanyl or Ketamine) Trial: A Randomized Controlled Trial Comparing Intranasal Ketamine and Fentanyl for the Relief of Moderate to Severe Pain in Children With Limb Injuries. YMEM. American College of Emergency Physicians; 2015 Mar 1;65(3):248–254.e1.
                      2. McQueen C, Crombie N, Cormack S, Wheaton S. Prehospital use of ketamine for analgesia and procedural sedation by critical care paramedics in the UK: a note of caution? Emergency Medicine Journal. 2014 Dec;31(12):1029.
                      3. Jennings PA, Cameron P, Bernard S, Walker T, Jolley D, Fitzgerald M, et al. Long-term pain prevalence and health-related quality of life outcomes for patients enrolled in a ketamine versus morphine for prehospital traumatic pain randomised controlled trial. Emergency Medicine Journal. 2014 Oct;31(10):840–3.
                      4. Andolfatto G, Abu-Laban RB, Zed PJ, Staniforth SM, Stackhouse S, Moadebi S, et al. Ketamine-propofol combination (ketofol) versus propofol alone for emergency department procedural sedation and analgesia: a randomized double-blind trial. Ann Emerg Med. 2012 Jun 1;59(6):504–12.e1–2.
                      5. Jennings PA, Cameron P, Bernard S, Walker T, Jolley D, Fitzgerald M, et al. Morphine and Ketamine Is Superior to Morphine Alone for Out-of-Hospital Trauma Analgesia: A Randomized Controlled Trial. Ann Emerg Med. 2012 Jan 11.
                      6. Bredmose PP, Lockey DJ, Grier G, Watts B, Davies G. Pre-hospital use of ketamine for analgesia and procedural sedation. Emerg Med J. 2009;26(1):62–4.
                      7. Howes MC. Ketamine for paediatric sedation/analgesia in the emergency department. Emerg Med J. 2004 May 1;21(3):275–80.
                      8. Porter K. Ketamine in prehospital care. Emerg Med J. 2004 May 1;21(3):351–4.
                      9. Gunning M, Perkins Z, Quinn T. Trench entrapment: is ketamine safe to use for sedation in head injury? Emerg Med J. 2007 Nov 1;24(11):794–5.
                      10. McGlone RG, Howes MC, Joshi M. The Lancaster experience of 2.0 to 2.5 mg/kg intramuscular ketamine for paediatric sedation: 501 cases and analysis. Emerg Med J. 2004 May 1;21(3):290–5.
                      11. Roback MG, Wathen JE, MacKenzie T, Bajaj L. A randomized, controlled trial of i.v. versus i.m. ketamine for sedation of pediatric patients receiving emergency department orthopedic procedures. Ann Emerg Med. 2006 Nov 1;48(5):605–12.
                      12. Newton A, Fitton L. Intravenous ketamine for adult procedural sedation in the emergency department: a prospective cohort study. Emerg Med J. 2008 Aug 1;25(8):498–501.
                      13. Chang LC. Raty SR. Ortiz J. Bailard NS. Mathew SJ. The Emerging Use of Ketamine for Anesthesia and Sedation in Traumatic Brain Injuries. CNS Neuroscience & Therapeutics. 2013; 19: 390–395
                      14. Morris C. Perris A. Klein J. Mahoney P. Anaesthesia in haemodynamically compromised emergency patients: does ketamine represent the best choice of induction agent? Anaesthesia. 2009; 64(5): 532-539.
                      15. 38 min
                      16. Episode 31: Stroke & Dizziness

                        https://phemcast.co.uk/wp-content/uploads/2019/01/stroke_final.mp3

                         

                        The Danish mnemonic to help remember the elements of a cerebellar neurological examination:

                        There are lots of Youtube videos to demonstrate these signs, here are a few which I thought were particularly helpful:

                        Disdiadochokinesis

                        Ataxia

                        Nystagmus

                        Intention tremor

                        If you would like to read more, there is a blog post Martin and I wrote here on the subject of dizziness, including some videos demonstrating elements of the HINTS exam, and another one from the St Emlyns team.

                        This is the paper Martin mentions.

                        Want to know more about stroke thrombolysis? Have a listen to this episode from our friends over at The Resus Room.

                        29 min
                      17. Episode 30: Head injury

                        https://phemcast.co.uk/wp-content/uploads/2018/10/head-injury_final.mp3

                        Quite a few of our previous podcasts include content which is relevant to this Head Injury one. Why not go back and have a listen to:

                        Episode 3: Hyperoxia

                        Episode 20: End Tidal Carbon Dioxide

                        Episode 28: LOST (Low Output State in Trauma)

                        Munroe-Kellie Doctrine

                        The Munroe-Kellie Doctrine is illustrated by the following pictures:

                        Or, alternatively, by Elfyn’s pint of Guinness analogy!

                        Autoregulation

                        Allows giraffes to drink from pools without a rush of blood to the head and eat leaves from trees without fainting.

                        This graph shows what happens to cerebral arterioles in uninjured brains, taken from Researchgate.net (Pires et al., 2013.)

                        Without autoregulation, in an injured brain, the arterioles will not change diameter in response to variations in blood pressure, and cerebral blood flow will have a linear relationship with blood pressure.

                        Cerebral perfusion pressure

                        Cerebral perfusion pressure = Mean arterial pressure – intracerebral pressure

                        The diameter of the arterioles, and therefore Cerebral perfusion pressure, is also affected by extremes of oxygen and carbon dioxide. If you would like to read more about this, have a look at this Life in The Fast Lane post.

                        References

                        The Brain Injury Foundation guidelines which Fliss mentions can be accessed here.

                        Doubts over head injury studies. Roberts I, Smith R, Evans S. BMJ. 2007 Feb 24; 334(7590): 392–394. (This is the paper Elfyn mentions regarding the now redacted original publications on the use of mannitol)

                        Wakai A, McCabe A, Roberts I, Schierhout G. Mannitol for acute traumatic brain injury. Cochrane Database of Systematic Reviews 2013, Issue 8. Art. No.: CD001049. DOI: 10.1002/14651858.CD001049.pub5

                        The HIRT trial: https://emj.bmj.com/content/32/11/869

                        The HITS-NS trial: The Head Injury Transportation Straight to Neurosurgery (HITS-NS) randomised trial: a feasibility study.

                        Wilson et al. Prognosis of patients with bilateral fixed dilated pupils secondary to traumatic extradural or subdural haematoma who undergo surgery: a systematic review and meta-analysis. 

                        Impact Brain Apnoea. https://www.ncbi.nlm.nih.gov/pubmed/27211834

                        And finally…

                        …. if you would like to hear more on the subject of Head Injury – have a listen to what the Resus Room team have to say about it:

                        46 min
                      18. Episode 29: Major Incidents

                        https://phemcast.co.uk/wp-content/uploads/2018/07/mi.mp3

                         

                        Another invitation to the Trauma Care Conference this year inspired us to combine two of the excellent speakers into this podcast considering major incidents. Thanks to both our speakers for sharing their talks from the conference.

                         

                        Trauma Care offer more than the annual conference; there are monthly webinars and regional meetings too, click here for more information.

                         

                         

                        The Joint Emergency Services Interoperability Programme (JESIP) website and National Ambulance Resilience Unit (NARU) website have lots of resources to support your response to a major incident.

                         

                        The papers which Chris mentions regarding IED injury patterns and management in children are both from the Journal of the Royal Army Medical Corps:

                        Thompson, Crooks, Clasper, Lupu, Stapely, Cloke. The pattern of paediatric blast injury in Afghanistan.

                        Ramasamy, Hill, Clasper. Improvised Explosive Devices: Pathophysiology, Injury Profiles and Current Medical Management

                         

                        46 min

                      About PHEMCAST

                      From the publisher's feed

                      A UK Prehospital Emergency Medicine Podcast.