In the new Apple TV+ series Physical, Rose Byrne plays a woman whose early '80s journey from miserable wife to powerhouse businesswoman goes directly through the fitness industry. Created by Annie Weisman, who used to write for Desperate Housewives, the show centers around Sheila Rubin, who despite being very beautiful, has a profoundly miserable relationship with her body, from bulimic behavior to an unrelentingly abusive interior monologue.